Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1051740
rs1051740
0.050 GeneticVariation BEFREE A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer. 21445251

2011

dbSNP: rs1051740
rs1051740
0.050 GeneticVariation BEFREE Quantitative assessment of the effects of the EPHX1 Tyr113His polymorphism on lung and breast cancer. 25222243

2014

dbSNP: rs1051740
rs1051740
0.050 GeneticVariation BEFREE The mEH polymorphisms Tyr113His and His139Arg are not risk factors for breast cancer. 24840637

2014

dbSNP: rs1051740
rs1051740
0.050 GeneticVariation BEFREE Thus, the Tyr113His and His139Arg mEH polymorphisms may not be risk factors for breast carcinoma. 25966185

2015

dbSNP: rs1051740
rs1051740
0.050 GeneticVariation BEFREE We undertook a case-control study in an Australian Caucasian population-based sample of 1,246 cases and 664 controls to assess the roles of detoxification gene polymorphisms EPHX T>C Tyr(113)His, GSTT1 deletion, GSTM1 deletion, and GSTP1 A>G Ile(105)Val on risk of breast cancer. 17416769

2007