| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | GeneticVariation | BEFREE | Our findings indicate that the GG genotype of rs12443621 is associated with increased breast cancer risk whereas the GA and AA genotypes of rs2981582 are reduced risk in Han Chinese population. | 26911390 | 2016 |
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0.070 | GeneticVariation | BEFREE | The study discovered for the first time that three SNPs (rs9933638, rs12443621, and rs3104746) at the TOX3/LOC643714 locus contributed to lung cancer risk, providing new evidences that lung cancer and breast cancer are linked at the molecular and genetic level to a certain extent. | 27486757 | 2016 |
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|
0.070 | GeneticVariation | BEFREE | We observed that the rs3803662 C > T, rs12443621 A > G and rs8051542 C > T were all correlated with increased risk of breast cancer. | 26239137 | 2015 |
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|
0.070 | GeneticVariation | BEFREE | The study results suggest that previously identified breast cancer risk susceptibility loci, rs12443621 (16q12) and rs6504950 (17q23), may influence breast cancer prognosis or comorbid conditions associated with overall survival. | 23635555 | 2013 |
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|
0.070 | GeneticVariation | BEFREE | There is no significant association between TNRC9 rs12443621 and rs8051542 polymorphisms and risk of breast cancer in current literature. | 20703937 | 2011 |
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0.070 | GeneticVariation | BEFREE | None of the three polymorphisms was significantly associated with breast cancer risk in the whole data set (P = 0.151, 0.644, and 0.737 for rs3803662, rs12443621. and rs8051542, respectively). | 20213080 | 2010 |
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|
0.070 | GeneticVariation | BEFREE | Interestingly, a significant interaction was detected between rs12443621A/G and ER status on breast cancer risk in a case-only analysis (P for interaction = 0.004). | 20213080 | 2010 |
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|
0.070 | GeneticVariation | BEFREE | The association with rs12443621 may provide clues as to how variation in TOX3 influences breast cancer risk. | 19232126 | 2009 |