Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2046210
rs2046210
0.900 GeneticVariation BEFREE In summary, our findings suggested that the rs2046210 polymorphism may serve as a potential genetic biomarker of BC in both Asians and Caucasians. 30693664

2019

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE TOX3-rs3803662, may confer some degrees of risk of breast cancer in Iranian population. 30515698

2019

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE SNP rs3803662 (TOX3/TNRC9) is an independent prognostic factor for breast cancer in Henan Han Population. 31317673

2019

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Significant associations with BC were observed for rs3803662 (dominant comparison: OR, 0.89; 95% CI, 0.84-0.95; P = .0008; recessive comparison: OR, 1.17; 95% CI, 1.07-1.28; P = .0004; over-dominant comparison: OR, 1.07; 95% CI, 1.02-1.11; P = .002; allele comparison: OR, 0.90; 95% CI, 0.86-0.95; P = .0002), rs8051542 (dominant comparison: OR, 0.87; 95% CI, 0.83-0.91; P < .0001; recessive comparison: OR, 1.19; 95% CI, 1.11-1.28; P < .0001; over-dominant comparison: OR, 1.07; 95% CI, 1.02-1.11; P = .004; allele comparison: OR, 0.89; 95% CI, 0.86-0.91; P < .0001), and rs12922061 (dominant comparison: OR, 0.83; 95% CI, 0.73-0.93; P = .002; over-dominant comparison: OR, 1.43; 95% CI, 1.27-1.61; P < .0001) polymorphisms in the overall population. 31324582

2019

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE This meta-analysis suggested that TOX3 rs3803662 polymorphism was associated with increased breast cancer risk. 29578175

2018

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE No statistically significant association was found between the rs3803662 polymorphism and breast cancer in patients or healthy controls. 29683073

2018

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Given that <i>TOX3</i> mRNA is a target of miR-182, and that both the <i>TOX3</i> rs3803662-T and pri-miR-182 rs4541843-T alleles are associated with increased BC risk, we evaluated their combined effect. 30135399

2018

dbSNP: rs17879961
rs17879961
G 0.900 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683

2017

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE BC patients (n = 1687) randomly sampled in an adjuvant, randomized phase III trial (SUCCESS A study) were genotyped for nine BC risk SNPs: rs17468277 <i>(CASP8)</i> , rs2981582 <i>(FGFR2)</i> , rs13281615(8q24), rs3817198 <i>(LSP1)</i> , rs889312 <i>(MAP3K1)</i> , rs3803662 <i>(TOX3)</i> , rs13387042(2q35), rs4973768 <i>(SLC4A7)</i> , rs6504950 <i>(COX11)</i> . 28757652

2017

dbSNP: rs17879961
rs17879961
0.900 GeneticVariation BEFREE A Comparison between CHEK2*1100delC/I157T Mutation Carrier and Noncarrier Breast Cancer Patients: A Clinicopathological Analysis. 26991782

2016

dbSNP: rs17879961
rs17879961
0.900 GeneticVariation BEFREE We analyzed the association between p.I157T and the clinico-pathological breast cancer characteristics by comparing the p.I157T carrier tumors to non-carrier and c.1100delC carrier tumors. 27716369

2016

dbSNP: rs2046210
rs2046210
A 0.900 GeneticVariation GWASCAT Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci. 27354352

2016

dbSNP: rs2046210
rs2046210
0.900 GeneticVariation BEFREE In a genome-wide association study conducted among Chinese women, we identified the single nucleotide polymorphism (SNP) rs2046210 at 6q25.1 for breast cancer risk. 26645718

2016

dbSNP: rs2046210
rs2046210
0.900 GeneticVariation BEFREE The genotype of rs2046210 (6q25.1), rs2981582 (EGFR2), rs889312 (MAP3K1), and rs3803662 (TOX3/TNRC9) has no statistical differences in different subtypes of breast cancer. 26803517

2016

dbSNP: rs2046210
rs2046210
0.900 GeneticVariation BEFREE The other two SNPs (rs2046210 and rs3734805) were strongly associated with susceptibility to breast cancer. 27525837

2016

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Five common breast cancer susceptibility loci from GWAS are not strongly associated with breast cancer risk among the Han Chinese of the Henan province; only rs3803662 (TOX3/TNRC9) is confirmed to increase the risk of breast cancer. 26803517

2016

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE Subjects carrying an allele of rs2981582 had reduced breast cancer risk (GA vs GG: OR=0.444, 95% CI=0.262-0.752; AA vs GG: OR=0.579, 95% CI=0.342-0.983). rs3803662 and rs3817198 SNPs did not significantly differ between cases and controls (P=0.408 and 0.116, respectively). 26911390

2016

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE The present meta-analysis suggests that rs3803662 polymorphism is significantly associated with breast cancer risk in Caucasian women, and we did not find the association in Asian women. 27350156

2016

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE The TNRC9 rs3803662 C>T polymorphism is greatly related to increased risk of BC, in both Asian and Caucasian populations. 27525937

2016

dbSNP: rs3803662
rs3803662
0.900 GeneticVariation BEFREE A case‑control study (90‑100 cases; 90‑100 controls) was performed to evaluate five genetic variants of three genes, including FGFR2 (SNPs: rs1219648, rs2981582), TNRC9 (SNPs: rs8051542, rs3803662) and MAP3K1 (SNP: rs889312) as BC risk factors in Pakistani women. 27572905

2016

dbSNP: rs17879961
rs17879961
G 0.900 GeneticVariation GWASCAT Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. 25751625

2015

dbSNP: rs2046210
rs2046210
A 0.900 GeneticVariation GWASCAT Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. 25751625

2015

dbSNP: rs2046210
rs2046210
0.900 GeneticVariation BEFREE Five of the 17 SNPs were significantly associated (P ≤ 0.05) with overall breast cancer in the same direction as previously reported: rs13387042 (2q35/TNP1), rs4973768 (3p24/SLC4A7), rs2046210 (6q25/ESR1), rs1219648 (10q26/FGFR2), and rs4784227 (16q12/TOX3). 24510657

2015

dbSNP: rs2046210
rs2046210
0.900 GeneticVariation BEFREE Furthermore, C6ORF97 showed significant worse prognostic values especially in luminal B subtype in the publically available data sets. rs2046210 and the upstream gene C6ORF97 might have substantial roles not only in carcinogenesis but also in progression toward a more aggressive phenotype in breast cancer patients, which suggests that functional studies of this locus are imperative. 25370037

2015

dbSNP: rs3803662
rs3803662
A 0.900 GeneticVariation GWASCAT Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. 25751625

2015