Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.060 | GeneticVariation | BEFREE | Join effect of three SNPs (PPP1R13L rs1970764, CD3EAP rs967591, GLTSCR1 rs1035938) on chromosome 19q13.3 showed that the designated haplotype8 (rs 1970764<sup>G</sup>-rs967591<sup>A</sup>-rs1035938<sup>C</sup>) [OR (95% CI)=1.60(1.11-2.32), P/0.012] andhaplotype8 (rs1970764<sup>G</sup>-rs967591<sup>G</sup>-rs1035938<sup>T</sup>) [OR (95% CI)=2.45 (1.17-5.12), P=0.018] were associated with increased risk of lung cancer (adjusted by smoking duration). | 30128886 | 2018 |
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0.060 | GeneticVariation | BEFREE | In conclusion, this study suggests that CD3EAP rs967</span>591 variant allele carriers are at increased susceptibility of lung cancer among nonsmoking Chinese women. | 23624123 | 2013 |
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0.060 | GeneticVariation | BEFREE | A functional variant at 19q13.3, rs967591G>A, is associated with shorter survival of early-stage lung cancer. | 23775331 | 2013 |
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0.060 | GeneticVariation | BEFREE | MDR (multifactor dimensionality reduction) analyses showed that smoking history as main effect and three-way models (smoking duration, 19p13.3-GADD45B rs3783501, 19q13.3-CD3EAP rs967591) (P = 0.001-0.002) indicated statistically significant association with lung cancer risk. | 28870783 | 2017 |
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0.060 | GeneticVariation | BEFREE | The common haplotype containing PPP1R13L rs1970764(G), CD3EAP rs967591(A), and CD3EAP rs735482(C) was associated with lung cancer [adjusted OR (95 % CI) = 1.29 (1.03-1.62), P = 0.028]. | 26563375 | 2016 |
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0.060 | GeneticVariation | BEFREE | In conclusion, we found that variant alleles of PPP1R13L rs1970764 and CD3EAP rs967591 may contribute to risk factors of lung cancer, but the high-risk diplotype predefined among Caucasians was rare and the diplotype is unlikely to confer lung cancer risk in a Chinese population. | 22335888 | 2012 |