Gene: BRAF ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs180177042
rs180177042
BRAF
T 0.700 GeneticVariation CLINVAR

dbSNP: rs387906660
rs387906660
BRAF
A 0.700 CausalMutation CLINVAR

dbSNP: rs387906661
rs387906661
BRAF
G 0.700 CausalMutation CLINVAR

dbSNP: rs397507466
rs397507466
BRAF
G 0.700 GeneticVariation CLINVAR

dbSNP: rs397516895
rs397516895
BRAF
T 0.700 GeneticVariation CLINVAR

dbSNP: rs113488022
rs113488022
BRAF
0.750 GeneticVariation BEFREE V599E BRAF mutation was uncommon in Japanese lung cancer. 16376942

2006
dbSNP: rs121913377
rs121913377
BRAF
0.050 GeneticVariation BEFREE V599E BRAF mutation was uncommon in Japanese lung cancer. 16376942

2006
dbSNP: rs113488022
rs113488022
BRAF
T 0.750 CausalMutation CLINVAR A patient with BRAF V600E lung adenocarcinoma responding to vemurafenib. 22743296

2012
dbSNP: rs113488022
rs113488022
BRAF
0.750 GeneticVariation BEFREE Accordingly, the combination of MEK inhibitor with EGFR inhibitor was effective at shrinking tumors in mouse model of BRAF non-V600E mutant lung cancer. 29348459

2018
dbSNP: rs121913377
rs121913377
BRAF
0.050 GeneticVariation BEFREE Accordingly, the combination of MEK inhibitor with EGFR inhibitor was effective at shrinking tumors in mouse model of BRAF non-V600E mutant lung cancer. 29348459

2018
dbSNP: rs121913351
rs121913351
BRAF
A 0.800 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210

2009
dbSNP: rs113488022
rs113488022
BRAF
T 0.750 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210

2009
dbSNP: rs1057519719
rs1057519719
BRAF
C 0.700 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210

2009
dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210

2009
dbSNP: rs121913355
rs121913355
BRAF
G 0.700 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210

2009
dbSNP: rs121913369
rs121913369
BRAF
C 0.700 CausalMutation CLINVAR Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. 19238210

2009
dbSNP: rs113488022
rs113488022
BRAF
0.750 GeneticVariation BEFREE BRAF V600E is an emerging drug target in lung cancer, but the clinical significance of non-V600 BRAF mutations in lung cancer and other malignancies is less clear. 24035431

2013
dbSNP: rs121913377
rs121913377
BRAF
0.050 GeneticVariation BEFREE BRAF V600E is an emerging drug target in lung cancer, but the clinical significance of non-V600 BRAF mutations in lung cancer and other malignancies is less clear. 24035431

2013
dbSNP: rs121913351
rs121913351
BRAF
A 0.800 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs113488022
rs113488022
BRAF
T 0.750 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs1057519719
rs1057519719
BRAF
C 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs1057519720
rs1057519720
BRAF
AA 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs121913355
rs121913355
BRAF
G 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs121913369
rs121913369
BRAF
C 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs121913369
rs121913369
BRAF
C 0.700 CausalMutation CLINVAR BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors. 22798288

2012