DisGeNET - a database of gene-disease associations

Carcinoma of lung, C0684249

Variant: rs3212986 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs3212986

ERCC1 ; CD3EAP

0.040

GeneticVariation

BEFREE

Conclusion We concluded that in lung cancer patients there is a relationship between tumor stage and rs3212986C>A polymorphism.

31245210

2019

dbSNP:

rs3212986

ERCC1 ; CD3EAP

0.040

GeneticVariation

BEFREE

The ERCC1 rs3212986 polymorphism was the most associated with the risk of developing lung cancer, both for low and high radon exposures.

31446980

2019

dbSNP:

rs3212986

ERCC1 ; CD3EAP

0.040

GeneticVariation

BEFREE

Particularly stratified by smoking status in cases and controls, A allele of ERCC1 rs3212986 also exhibited an enhanced risk to develop lung cancer in smokers only (P < 0.05).

30453383

2018

dbSNP:

rs3212986

ERCC1 ; CD3EAP

0.040

GeneticVariation

BEFREE

An updated meta-analysis was conducted to explore whether lung cancer risk could be attributed to the following ERCC1 polymorphisms: rs11615 (T>C), rs3212986 (C>A), rs3212961 (A>C), rs3212948 (G>C), rs2298881 (C>A).

24841208

2014