Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587782705
rs587782705
A 0.700 CausalMutation CLINVAR

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE TP53 p.R72P genotype is a marker of poor prognosis in lung cancer. 29286914

2018

dbSNP: rs1131691014
rs1131691014
0.100 GeneticVariation BEFREE TP53 p.R72P genotype is a marker of poor prognosis in lung cancer. 29286914

2018

dbSNP: rs878854066
rs878854066
0.100 GeneticVariation BEFREE TP53 p.R72P genotype is a marker of poor prognosis in lung cancer. 29286914

2018

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE Twenty-two variants from 21 genes (APEX1 rs1130409 and rs1760944, ATM rs664677, AXIN2 rs2240308, CHRNA3 rs6495309, CHRNA5 rs16969968, CLPTM1L rs402710, CXCR2 rs1126579, CYP1A1 rs4646903, CYP2E1 rs6413432, ERCC1 rs11615, ERCC2 rs13181, FGFR4 rs351855, HYKK rs931794, MIR146A rs2910164, MIR196A2 rs11614913, OGG1 rs1052133, PON1 rs662, REV3L rs462779, SOD2 rs4880, TERT rs2736098, and TP53 rs1042522) showed significant associations with lung cancer susceptibility with strong cumulative epidemiological evidence. 28827732

2017

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE We conclude that not Pro47Ser SNP but Arg72Pro SNP is involved in susceptibility to developing lung cancer, at least in Bangladeshi population. 25034526

2014

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE We used real-time PCR method to investigate the genotypic frequencies of rs2602141, rs560191 and rs689647 in 53BP1 and rs1042522 in TP53 in 640 cases of lung cancer and 685 controls. 24316395

2014

dbSNP: rs1131691014
rs1131691014
0.100 GeneticVariation BEFREE We conclude that not Pro47Ser SNP but Arg72Pro SNP is involved in susceptibility to developing lung cancer, at least in Bangladeshi population. 25034526

2014

dbSNP: rs878854066
rs878854066
0.100 GeneticVariation BEFREE We conclude that not Pro47Ser SNP but Arg72Pro SNP is involved in susceptibility to developing lung cancer, at least in Bangladeshi population. 25034526

2014

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE Present report evaluated the association of polymorphism in exon 4 Arg72Pro (G>C) of the p53 gene with lung cancer susceptibility using 175 cancer cases and 202 controls from the North Indian population. 23317414

2013

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE The variant genotype of TP53 SNP rs1042522 significantly increased lung cancer risk in the total population (OR: 1.57, 95% CI: 1.11-2.21), but there was no evidence of heterogeneity among individuals with different lifestyle factors. 24369748

2013

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE We performed a meta-analysis to evaluate the relationship between TP53 Arg72Pro polymorphism and lung cancer susceptibility basing on 15,647 lung cancer patients and 14,391 controls from 36 published literatures. 23595658

2013

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE The updated meta-analysis suggests that the p53 codon 72 Arg/Pro polymorphism is a risk factor for lung cancer in the Asian population. 23812725

2013

dbSNP: rs1131691014
rs1131691014
0.100 GeneticVariation BEFREE Present report evaluated the association of polymorphism in exon 4 Arg72Pro (G>C) of the p53 gene with lung cancer susceptibility using 175 cancer cases and 202 controls from the North Indian population. 23317414

2013

dbSNP: rs1131691014
rs1131691014
0.100 GeneticVariation BEFREE We performed a meta-analysis to evaluate the relationship between TP53 Arg72Pro polymorphism and lung cancer susceptibility basing on 15,647 lung cancer patients and 14,391 controls from 36 published literatures. 23595658

2013

dbSNP: rs1131691014
rs1131691014
0.100 GeneticVariation BEFREE The updated meta-analysis suggests that the p53 codon 72 Arg/Pro polymorphism is a risk factor for lung cancer in the Asian population. 23812725

2013

dbSNP: rs878854066
rs878854066
0.100 GeneticVariation BEFREE The updated meta-analysis suggests that the p53 codon 72 Arg/Pro polymorphism is a risk factor for lung cancer in the Asian population. 23812725

2013

dbSNP: rs878854066
rs878854066
0.100 GeneticVariation BEFREE We performed a meta-analysis to evaluate the relationship between TP53 Arg72Pro polymorphism and lung cancer susceptibility basing on 15,647 lung cancer patients and 14,391 controls from 36 published literatures. 23595658

2013

dbSNP: rs878854066
rs878854066
0.100 GeneticVariation BEFREE Present report evaluated the association of polymorphism in exon 4 Arg72Pro (G>C) of the p53 gene with lung cancer susceptibility using 175 cancer cases and 202 controls from the North Indian population. 23317414

2013

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE More studies stratified for lung cancer stage-genotyping interaction should be performed to clarify the role of TP53 Arg72Pro polymorphism in the development of lung cancer. 19623649

2009

dbSNP: rs1042522
rs1042522
0.100 GeneticVariation BEFREE The polymorphic frequency of 10 genetic susceptibility genes and their association with lung cancer were examined in a northern Thai population: CYP1A1 (MspI), CYP1A1 (Ile462Val), CYP2E1 (PstI), CYP2E1 (DraI), GSTM1, GSTT1, MPO (AciI), OGG1 (Ser326Cys), TP53 (Arg72Pro), and MMP1(AluI). 19963114

2009

dbSNP: rs1131691014
rs1131691014
0.100 GeneticVariation BEFREE The polymorphic frequency of 10 genetic susceptibility genes and their association with lung cancer were examined in a northern Thai population: CYP1A1 (MspI), CYP1A1 (Ile462Val), CYP2E1 (PstI), CYP2E1 (DraI), GSTM1, GSTT1, MPO (AciI), OGG1 (Ser326Cys), TP53 (Arg72Pro), and MMP1(AluI). 19963114

2009

dbSNP: rs1131691014
rs1131691014
0.100 GeneticVariation BEFREE More studies stratified for lung cancer stage-genotyping interaction should be performed to clarify the role of TP53 Arg72Pro polymorphism in the development of lung cancer. 19623649

2009

dbSNP: rs878854066
rs878854066
0.100 GeneticVariation BEFREE The polymorphic frequency of 10 genetic susceptibility genes and their association with lung cancer were examined in a northern Thai population: CYP1A1 (MspI), CYP1A1 (Ile462Val), CYP2E1 (PstI), CYP2E1 (DraI), GSTM1, GSTT1, MPO (AciI), OGG1 (Ser326Cys), TP53 (Arg72Pro), and MMP1(AluI). 19963114

2009

dbSNP: rs878854066
rs878854066
0.100 GeneticVariation BEFREE More studies stratified for lung cancer stage-genotyping interaction should be performed to clarify the role of TP53 Arg72Pro polymorphism in the development of lung cancer. 19623649

2009