Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800734
rs1800734
0.040 GeneticVariation BEFREE In the subgroup analysis by cancer type, we found a moderate association between rs1800734 and the risk of gastric cancer (allele model: OR = 1.14, P = 0.017; homozygote model: OR = 1.33, P = 0.019; dominant model: OR = 1.27, P = 0.024) and lung cancer in recessive model (OR = 1.27, P = 0.024). 29190978

2017

dbSNP: rs1800734
rs1800734
0.040 GeneticVariation BEFREE We unravelled a potential for increased risk of lung cancer development in the hMLH1 (rs1800734) AA genotype in the recessive model. 26987333

2016

dbSNP: rs1800734
rs1800734
0.040 GeneticVariation BEFREE The evaluation of rs1800734 polymorphism in patients in the dominant model showed a significantly decreased risk of lung cancer in the presence of at least one variant allele A (genotype GA and AA) (OR=1.40; 95% CI=1.08-1.82; p=0.01). 25252909

2015

dbSNP: rs1800734
rs1800734
0.040 GeneticVariation BEFREE Among the SNP polymorphisms, -93A>G (rs1800734), which is located in the promoter region of MLH1, was significantly associated with the risk of lung cancer. 21093954

2011

dbSNP: rs876658657
rs876658657
0.030 GeneticVariation BEFREE In conclusion, our data suggest that the MLH1 -93A>G polymorphism may contribute to the etiology of lung cancer, particularly in never smokers. 21093954

2011

dbSNP: rs876658657
rs876658657
0.030 GeneticVariation BEFREE A polymorphism in the hMLH1 gene (-93G-->A) associated with lung cancer susceptibility and prognosis. 19956916

2010

dbSNP: rs876658657
rs876658657
0.030 GeneticVariation BEFREE -93G-->A polymorphism of hMLH1 and risk of primary lung cancer. 15382050

2004

dbSNP: rs1799977
rs1799977
0.010 GeneticVariation BEFREE Overall, the rs1799977 I219V polymorphism was marginally associated with the risk of lung cancer (P=0.055). 17870204

2008

dbSNP: rs63750447
rs63750447
0.010 GeneticVariation BEFREE To our knowledge, this is for the first time that the T1151A mutation is found in lung cancer. 12874865

2003