rs1800734
|
|
|
0.040 |
GeneticVariation |
BEFREE |
In the subgroup analysis by cancer type, we found a moderate association between rs1800734 and the risk of gastric cancer (allele model: OR = 1.14, P = 0.017; homozygote model: OR = 1.33, P = 0.019; dominant model: OR = 1.27, P = 0.024) and lung cancer in recessive model (OR = 1.27, P = 0.024).
|
29190978 |
2017 |
rs1800734
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We unravelled a potential for increased risk of lung cancer development in the hMLH1 (rs1800734) AA genotype in the recessive model.
|
26987333 |
2016 |
rs1800734
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The evaluation of rs1800734 polymorphism in patients in the dominant model showed a significantly decreased risk of lung cancer in the presence of at least one variant allele A (genotype GA and AA) (OR=1.40; 95% CI=1.08-1.82; p=0.01).
|
25252909 |
2015 |
rs1800734
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Among the SNP polymorphisms, -93A>G (rs1800734), which is located in the promoter region of MLH1, was significantly associated with the risk of lung cancer.
|
21093954 |
2011 |
rs876658657
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In conclusion, our data suggest that the MLH1 -93A>G polymorphism may contribute to the etiology of lung cancer, particularly in never smokers.
|
21093954 |
2011 |
rs876658657
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A polymorphism in the hMLH1 gene (-93G-->A) associated with lung cancer susceptibility and prognosis.
|
19956916 |
2010 |
rs876658657
|
|
|
0.030 |
GeneticVariation |
BEFREE |
-93G-->A polymorphism of hMLH1 and risk of primary lung cancer.
|
15382050 |
2004 |
rs1799977
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overall, the rs1799977 I219V polymorphism was marginally associated with the risk of lung cancer (P=0.055).
|
17870204 |
2008 |
rs63750447
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To our knowledge, this is for the first time that the T1151A mutation is found in lung cancer.
|
12874865 |
2003 |