Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
---|---|---|---|---|---|---|---|---|---|---|
|
C | 0.810 | CausalMutation | CLINVAR | ||||||
|
C | 0.800 | CausalMutation | CLINVAR | ||||||
|
T | 0.800 | CausalMutation | CLINVAR | ||||||
|
G | 0.800 | CausalMutation | CLINVAR | ||||||
|
G | 0.800 | CausalMutation | CLINVAR | ||||||
|
T | 0.700 | GeneticVariation | CLINVAR | ||||||
|
A | 0.700 | GeneticVariation | CLINVAR | ||||||
|
C | 0.700 | CausalMutation | CLINVAR | ||||||
|
A | 0.700 | CausalMutation | CLINVAR | ||||||
|
G | 0.700 | CausalMutation | CLINVAR | ||||||
|
T | 0.700 | CausalMutation | CLINVAR | ||||||
|
C | 0.700 | CausalMutation | CLINVAR | ||||||
|
T | 0.700 | CausalMutation | CLINVAR | ||||||
|
C | 0.700 | CausalMutation | CLINVAR | ||||||
|
C | 0.700 | CausalMutation | CLINVAR | ||||||
|
T | 0.700 | CausalMutation | CLINVAR | A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis. | 15316116 | 2004 |
|||
|
T | 0.700 | CausalMutation | CLINVAR | Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate. | 20133659 | 2010 |
|||
|
C | 0.710 | CausalMutation | CLINVAR | Apert and Crouzon syndromes-Cognitive development, brain abnormalities, and molecular aspects. | 27028366 | 2016 |
|||
|
0.800 | GeneticVariation | UNIPROT | Clinical findings in a patient with FGFR1 P252R mutation and comparison with the literature. | 10861678 | 2000 |
||||
|
C | 0.710 | CausalMutation | CLINVAR | Clustering of FGFR2 gene mutations inpatients with Pfeiffer and Crouzon syndromes (FGFR2-associated craniosynostoses). | 11173845 | 2000 |
|||
|
C | 0.710 | CausalMutation | CLINVAR | Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras. | 8755573 | 1996 |
|||
|
T | 0.700 | CausalMutation | CLINVAR | Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras. | 8755573 | 1996 |
|||
|
0.810 | GeneticVariation | UNIPROT | Description of a new mutation and characterization of FGFR1, FGFR2, and FGFR3 mutations among Brazilian patients with syndromic craniosynostoses. | 9677057 | 1998 |
||||
|
0.800 | GeneticVariation | UNIPROT | Description of a new mutation and characterization of FGFR1, FGFR2, and FGFR3 mutations among Brazilian patients with syndromic craniosynostoses. | 9677057 | 1998 |
||||
|
0.800 | GeneticVariation | UNIPROT | Description of a new mutation and characterization of FGFR1, FGFR2, and FGFR3 mutations among Brazilian patients with syndromic craniosynostoses. | 9677057 | 1998 |