|
rs12150220
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Data showed that the NLRP1 rs12150220 missense variant (H155L) was significantly correlated with numbers of ABs in MPM patients.
|
29265930 |
2018 |
|
rs243865
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The <i>MMP2</i> rs243865 polymorphism may have a protective role in malignant pleural mesothelioma development.
|
30018519 |
2018 |
|
rs9939609
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study shows for the first time that rs9939609 polymorphism in the FTO gene may be a genetic risk factor for MPM.
|
29260910 |
2018 |
|
rs2235503
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found a strong association between serum SMRP and variant alleles of rs3764247, rs3764246 (in strong linkage disequilibrium with rs2235504) and rs2235503 in non-MPM subjects.
|
28343162 |
2017 |
|
rs2235504
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found a strong association between serum SMRP and variant alleles of rs3764247, rs3764246 (in strong linkage disequilibrium with rs2235504) and rs2235503 in non-MPM subjects.
|
28343162 |
2017 |
|
rs3764246
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found a strong association between serum SMRP and variant alleles of rs3764247, rs3764246 (in strong linkage disequilibrium with rs2235504) and rs2235503 in non-MPM subjects.
|
28343162 |
2017 |
|
rs3764247
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found a strong association between serum SMRP and variant alleles of rs3764247, rs3764246 (in strong linkage disequilibrium with rs2235504) and rs2235503 in non-MPM subjects.
|
28343162 |
2017 |
|
rs28934574
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that the MPM had R282W, a key TP53 mutation, and genome-wide allelic loss or loss of heterozygosity, a distinct genomic alteration not previously described in MPM.
|
26824986 |
2016 |
|
rs1508805
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GMDR analysis showed a strong MPM risk due to asbestos exposure and suggested a possible synergistic effect between asbestos exposure and rs1508805, rs2501618 and rs5756444.
|
26139392 |
2015 |
|
rs2501618
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GMDR analysis showed a strong MPM risk due to asbestos exposure and suggested a possible synergistic effect between asbestos exposure and rs1508805, rs2501618 and rs5756444.
|
26139392 |
2015 |
|
rs5756444
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GMDR analysis showed a strong MPM risk due to asbestos exposure and suggested a possible synergistic effect between asbestos exposure and rs1508805, rs2501618 and rs5756444.
|
26139392 |
2015 |
|
rs12947788
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, TP53 polymorphisms in intron 7 (rs12947788 and rs12951053) were more frequently identified in asbestos-exposed NSCLC (P = 0.046) and MPM patients than in unexposed patients (P < 0.001 and P = 0.012, respectively).
|
23435014 |
2013 |
|
rs12951053
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, TP53 polymorphisms in intron 7 (rs12947788 and rs12951053) were more frequently identified in asbestos-exposed NSCLC (P = 0.046) and MPM patients than in unexposed patients (P < 0.001 and P = 0.012, respectively).
|
23435014 |
2013 |
|
rs16906252
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Thirteen of the 95 MPM samples (13.7%) were methylation positive and a strong association with the T allele of the rs16906252 SNP (P<0.001) was observed.
|
20627446 |
2011 |
|
rs1041983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
On the other hand, the nucleotidic change 282C>T within NAT2 held the statistical significance (OR=3.54; 95% CI 1.75-7.16; p=0.0002), reinforcing existing evidences that describe genetic polymorphisms of NAT2 possibly involved in the etiology of the MPM.
|
19751749 |
2009 |