Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8028958
rs8028958
0.710 GeneticVariation GWASCAT We observed strong association between candidemia and a variant, rs8028958, that significantly affects the expression levels of PLA2G4B in blood. 31241743

2019

dbSNP: rs8028958
rs8028958
0.710 GeneticVariation BEFREE We observed strong association between candidemia and a variant, rs8028958, that significantly affects the expression levels of PLA2G4B in blood. 31241743

2019

dbSNP: rs16910526
rs16910526
0.030 GeneticVariation BEFREE Screening for the DECTIN-1 Y238X polymorphism within a group of 142 patients undergoing HSCT was correlated with Candida colonization and candidemia. 19614557

2009

dbSNP: rs16910526
rs16910526
0.030 GeneticVariation BEFREE No significant association between the single-nucleotide polymorphisms DECTIN-1 Y238X and CARD9 S12N and the prevalence of candidemia was found, despite the association of the DECTIN-1 238X allele with impaired in vitro and in vivo cytokine production. 21881131

2011

dbSNP: rs16910526
rs16910526
0.030 GeneticVariation BEFREE The role of Candida species herein has recently been rediscovered since a 'loss-of-function' Y238X polymorphism in dectin-1, a C-type lectin receptor recognizing the β-1,3-glucan motif of Candida, resulted in diminished membrane expression and lower cytokine responses upon β-1,3-glucan recognition, and was associated with increased Candida colonization of SCT recipients, rendering them at risk for candidaemia. 21178438

2011

dbSNP: rs1196547982
rs1196547982
0.010 GeneticVariation BEFREE Analyses of TLR SNPs revealed that 3 TLR1 SNPs (R80T, S248N, I602S) were significantly associated with candidemia susceptibility in whites. 22301633

2012

dbSNP: rs1800896
rs1800896
0.010 GeneticVariation BEFREE In the multivariable model, persistent candidemia was significantly associated with (odds ratio [95% confidence interval]): total parenteral nutrition (2.79 [1.26-6.17]), dialysis dependence (3.76 [1.46-8.64]), and the SNPs IL10 rs1800896 (3.45 [1.33-8.93]) and IL12B rs41292470 (5.36 [1.51-19.0]). 22144535

2012

dbSNP: rs4077515
rs4077515
0.010 GeneticVariation BEFREE No significant association between the single-nucleotide polymorphisms DECTIN-1 Y238X and CARD9 S12N and the prevalence of candidemia was found, despite the association of the DECTIN-1 238X allele with impaired in vitro and in vivo cytokine production. 21881131

2011

dbSNP: rs41292470
rs41292470
0.010 GeneticVariation BEFREE In the multivariable model, persistent candidemia was significantly associated with (odds ratio [95% confidence interval]): total parenteral nutrition (2.79 [1.26-6.17]), dialysis dependence (3.76 [1.46-8.64]), and the SNPs IL10 rs1800896 (3.45 [1.33-8.93]) and IL12B rs41292470 (5.36 [1.51-19.0]). 22144535

2012

dbSNP: rs4833095
rs4833095
0.010 GeneticVariation BEFREE Analyses of TLR SNPs revealed that 3 TLR1 SNPs (R80T, S248N, I602S) were significantly associated with candidemia susceptibility in whites. 22301633

2012

dbSNP: rs4986790
rs4986790
0.010 GeneticVariation BEFREE IL-10 production was higher in C. albicans-stimulated PBMC from volunteers bearing the TLR4 Asp299Gly polymorphism, and a similar tendency was observed in TLR4 Asp299Gly heterozygous patients who had recovered from candidemia. 16613760

2006

dbSNP: rs5743618
rs5743618
0.010 GeneticVariation BEFREE Analyses of TLR SNPs revealed that 3 TLR1 SNPs (R80T, S248N, I602S) were significantly associated with candidemia susceptibility in whites. 22301633

2012

dbSNP: rs748327912
rs748327912
0.010 GeneticVariation BEFREE No significant association between the single-nucleotide polymorphisms DECTIN-1 Y238X and CARD9 S12N and the prevalence of candidemia was found, despite the association of the DECTIN-1 238X allele with impaired in vitro and in vivo cytokine production. 21881131

2011

dbSNP: rs775910328
rs775910328
0.010 GeneticVariation BEFREE Analyses of TLR SNPs revealed that 3 TLR1 SNPs (R80T, S248N, I602S) were significantly associated with candidemia susceptibility in whites. 22301633

2012