rs8028958
|
|
|
0.710 |
GeneticVariation |
GWASCAT |
We observed strong association between candidemia and a variant, rs8028958, that significantly affects the expression levels of PLA2G4B in blood.
|
31241743 |
2019 |
rs8028958
|
|
|
0.710 |
GeneticVariation |
BEFREE |
We observed strong association between candidemia and a variant, rs8028958, that significantly affects the expression levels of PLA2G4B in blood.
|
31241743 |
2019 |
rs16910526
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Screening for the DECTIN-1 Y238X polymorphism within a group of 142 patients undergoing HSCT was correlated with Candida colonization and candidemia.
|
19614557 |
2009 |
rs16910526
|
|
|
0.030 |
GeneticVariation |
BEFREE |
No significant association between the single-nucleotide polymorphisms DECTIN-1 Y238X and CARD9 S12N and the prevalence of candidemia was found, despite the association of the DECTIN-1 238X allele with impaired in vitro and in vivo cytokine production.
|
21881131 |
2011 |
rs16910526
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The role of Candida species herein has recently been rediscovered since a 'loss-of-function' Y238X polymorphism in dectin-1, a C-type lectin receptor recognizing the β-1,3-glucan motif of Candida, resulted in diminished membrane expression and lower cytokine responses upon β-1,3-glucan recognition, and was associated with increased Candida colonization of SCT recipients, rendering them at risk for candidaemia.
|
21178438 |
2011 |
rs1196547982
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analyses of TLR SNPs revealed that 3 TLR1 SNPs (R80T, S248N, I602S) were significantly associated with candidemia susceptibility in whites.
|
22301633 |
2012 |
rs1800896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the multivariable model, persistent candidemia was significantly associated with (odds ratio [95% confidence interval]): total parenteral nutrition (2.79 [1.26-6.17]), dialysis dependence (3.76 [1.46-8.64]), and the SNPs IL10 rs1800896 (3.45 [1.33-8.93]) and IL12B rs41292470 (5.36 [1.51-19.0]).
|
22144535 |
2012 |
rs4077515
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant association between the single-nucleotide polymorphisms DECTIN-1 Y238X and CARD9 S12N and the prevalence of candidemia was found, despite the association of the DECTIN-1 238X allele with impaired in vitro and in vivo cytokine production.
|
21881131 |
2011 |
rs41292470
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the multivariable model, persistent candidemia was significantly associated with (odds ratio [95% confidence interval]): total parenteral nutrition (2.79 [1.26-6.17]), dialysis dependence (3.76 [1.46-8.64]), and the SNPs IL10 rs1800896 (3.45 [1.33-8.93]) and IL12B rs41292470 (5.36 [1.51-19.0]).
|
22144535 |
2012 |
rs4833095
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analyses of TLR SNPs revealed that 3 TLR1 SNPs (R80T, S248N, I602S) were significantly associated with candidemia susceptibility in whites.
|
22301633 |
2012 |
rs4986790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-10 production was higher in C. albicans-stimulated PBMC from volunteers bearing the TLR4 Asp299Gly polymorphism, and a similar tendency was observed in TLR4 Asp299Gly heterozygous patients who had recovered from candidemia.
|
16613760 |
2006 |
rs5743618
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analyses of TLR SNPs revealed that 3 TLR1 SNPs (R80T, S248N, I602S) were significantly associated with candidemia susceptibility in whites.
|
22301633 |
2012 |
rs748327912
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant association between the single-nucleotide polymorphisms DECTIN-1 Y238X and CARD9 S12N and the prevalence of candidemia was found, despite the association of the DECTIN-1 238X allele with impaired in vitro and in vivo cytokine production.
|
21881131 |
2011 |
rs775910328
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analyses of TLR SNPs revealed that 3 TLR1 SNPs (R80T, S248N, I602S) were significantly associated with candidemia susceptibility in whites.
|
22301633 |
2012 |