Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs113488022
rs113488022
0.750 GeneticVariation BEFREE Sustained response to vemurafenib in a low grade serous ovarian cancer with a BRAF V600E mutation. 26490654

2015

dbSNP: rs113488022
rs113488022
0.750 GeneticVariation BEFREE In this study, we compared detection of the V600E mutation in serous ovarian tumors by VE1 immunostaining and by allele-specific polymerase chain reaction. 23089489

2013

dbSNP: rs113488022
rs113488022
0.750 GeneticVariation BEFREE The presence of the BRAF V600E mutation in SB/LGS ovarian cancer was associated with early stage disease and improved prognosis. 22930283

2013

dbSNP: rs113488022
rs113488022
0.750 GeneticVariation BEFREE No BRAF V600E mutations were detected in nonserous epithelial ovarian tumors. 22820660

2013

dbSNP: rs113488022
rs113488022
T 0.750 CausalMutation CLINVAR Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. 22608338

2012

dbSNP: rs113488022
rs113488022
T 0.750 CausalMutation CLINVAR Improved survival with vemurafenib in melanoma with BRAF V600E mutation. 21639808

2011

dbSNP: rs113488022
rs113488022
T 0.750 CausalMutation CLINVAR Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. 21683865

2011

dbSNP: rs113488022
rs113488022
T 0.750 CausalMutation CLINVAR Epidermal growth factor receptor blockers for the treatment of ovarian cancer. 21975775

2011

dbSNP: rs113488022
rs113488022
0.750 GeneticVariation BEFREE One recurrent somatic mutation, p.V600E, is frequently found in several tumor types, such as melanoma, papillary thyroid carcinoma, colon cancer, and ovarian cancer. 20735442

2011

dbSNP: rs113488022
rs113488022
T 0.750 CausalMutation CLINVAR Inhibition of mutated, activated BRAF in metastatic melanoma. 20818844

2010

dbSNP: rs113488022
rs113488022
T 0.750 CausalMutation CLINVAR KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer. 19018267

2008

dbSNP: rs113488022
rs113488022
T 0.750 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002