|
rs2910164
|
|
|
0.080 |
GeneticVariation |
BEFREE |
BACKGROUND The association between 3 well known SNPs - miR-146a C/G (rs2910164), miR-196a2 T/C (rs11614913), and miR-499 A/G (rs3746444) - in pre-miRNA sequences and ischemic stroke (IS) are still conflicting and inconclusive.
|
26608782 |
2015 |
|
rs2910164
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In conclusion, the current meta-analysis suggests lower risks of CAD for GG, GG + GC genotype and G allele of rs2910164, while rs2910164 is not associated with the risk of IS.
|
26114385 |
2015 |
|
rs2910164
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In this study, we investigated the associations between SNPs in miRNAs and IS including rs2910164, rs11614913, and rs3746444 in a Korean population.
|
31781304 |
2019 |
|
rs2910164
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We evaluated the associations of the hsa-mir-196-a2/rs11614913 T/C, hsa-mir-146a/rs2910164 C/G, and hsa-mir-499/rs3746444 A/G polymorphisms in pre-miRNAs with the risk of ischemic stroke in a Chinese population.
|
24178064 |
2014 |
|
rs2910164
|
|
|
0.080 |
GeneticVariation |
BEFREE |
These results indicate that the GG genotype of miR-146a (rs2910164) and CC genotype of miR-149 (rs2292832) may confer increased susceptibility to IS, while miR-196a2 (rs11614913) and miR-499 (rs3746444) polymorphisms may not be associated with IS risk in Asian populations.
|
30254431 |
2018 |
|
rs2910164
|
|
|
0.080 |
GeneticVariation |
BEFREE |
This study indicates that miR-146a (rs2910164) might contribute to ischemic stroke susceptibility in the northern Chinese Han population.
|
24952884 |
2014 |
|
rs2910164
|
|
|
0.080 |
GeneticVariation |
BEFREE |
No significant association was observed between miR-146a C>G (rs2910164), miR-149 T>C (rs2292832), miR-196a2 T>C (rs11614913), and IS risk.
|
29643803 |
2018 |
|
rs2910164
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In summary, this study provides evidence that miR-146a/rs2910164 might be associated with a significantly increased risk of ischemic stroke</span> in a Chinese population, and the combined effects between miRNA polymorphism and fasting glucose /blood lipid levels may contribute to stroke pathogenesis.
|
25658319 |
2015 |