Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6025
rs6025
F5
0.740 GeneticVariation BEFREE A total of nine gene variants/polymorphisms - F5 (Leiden - R5 06Q, rs6025), F2 (20210G > A, rs1799963), F13A1 (V34L, rs5985), MTHFR (677C > T - A222V, rs1801133), MTHFR (1298A > C - E429A, rs1801131), FGB (-455G > A -c.-463G > A; rs1800790), SERPINE1 (PAI14G/5G - rs1799889), ACE (ACE I/D, rs1799752), ITGB3 (GPIIIa L33P, rs5918) and the APOE E2/E3/E4 alleles (rs7412, rs429358) - were genotyped in 200 newly diagnosed ischemic stroke (IS) patients, 165 patients with ischemic coronary heart disease (CHD) and 159 controls with no cerebroor cardiovascular disease (non-CVD). 27629735

2016

dbSNP: rs6025
rs6025
F5
T 0.740 GeneticVariation GWASCAT Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis. 26908601

2016

dbSNP: rs6025
rs6025
F5
0.740 GeneticVariation BEFREE There was no association of rs6025 with IS in general, or with any subtype. 25897999

2015

dbSNP: rs6025
rs6025
F5
0.740 GeneticVariation BEFREE Activated protein C resistance in ischemic stroke not due to factor V arginine506-->glutamine mutation. 8685921

1996

dbSNP: rs6025
rs6025
F5
0.740 GeneticVariation BEFREE The common factor V Arg 506 Gln mutation predisposing to venous thrombosis is not a significant genetic risk factor for ischemic stroke in the elderly. 8553401

1996

dbSNP: rs2200733
rs2200733
T 0.730 GeneticVariation GWASCAT Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. 26708676

2016

dbSNP: rs2200733
rs2200733
0.730 GeneticVariation BEFREE Our results show that the SNP rs2200733</span> and r</span>s6843082 have no significant associations with IS in additive, dominant, recessive, and allelic models (all p > 0.050). 25711478

2015

dbSNP: rs2200733
rs2200733
0.730 GeneticVariation BEFREE No significant association was found between rs2200733 and ischemic stroke. 19707791

2009

dbSNP: rs2200733
rs2200733
0.730 GeneticVariation BEFREE We discovered that variants previously shown to associate with atrial fibrillation (AF), rs2200733 and rs10033464, significantly associated with IS, with the strongest risk for CES. 18991354

2008

dbSNP: rs10744777
rs10744777
0.720 GeneticVariation BEFREE The genotype of rs10744777 (CT/TT) was associated with risk of ischemic stroke in males (OR = 1.99, 95% CI = 1.15-3.42, P = 0.013). 30077765

2018

dbSNP: rs505922
rs505922
ABO
0.720 GeneticVariation BEFREE We found that rs579459 and rs505922 within ABO gene and their interaction were both associated with increased IS risk in Chinese population. 28984382

2018

dbSNP: rs529565
rs529565
ABO
0.720 GeneticVariation BEFREE We did not find any relation of rs651007 and rs529565 with IS risk in both additive and dominant models. 28984382

2018

dbSNP: rs505922
rs505922
ABO
C 0.720 GeneticVariation GWASCAT Genetic Drivers of von Willebrand Factor Levels in an Ischemic Stroke Population and Association With Risk for Recurrent Stroke. 28495826

2017

dbSNP: rs10744777
rs10744777
T 0.720 GeneticVariation GWASCAT Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. 26708676

2016

dbSNP: rs1799963
rs1799963
F2
0.720 GeneticVariation BEFREE A total of nine gene variants/polymorphisms - F5 (Leiden - R5 06Q, rs6025), F2 (20210G > A, rs1799963), F13A1 (V34L, rs5985), MTHFR (677C > T - A222V, rs1801133), MTHFR (1298A > C - E429A, rs1801131), FGB (-455G > A -c.-463G > A; rs1800790), SERPINE1 (PAI14G/5G - rs1799889), ACE (ACE I/D, rs1799752), ITGB3 (GPIIIa L33P, rs5918) and the APOE E2/E3/E4 alleles (rs7412, rs429358) - were genotyped in 200 newly diagnosed ischemic stroke (IS) patients, 165 patients with ischemic coronary heart disease (CHD) and 159 controls with no cerebroor cardiovascular disease (non-CVD). 27629735

2016

dbSNP: rs1799963
rs1799963
F2
A 0.720 GeneticVariation GWASCAT Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis. 26908601

2016

dbSNP: rs529565
rs529565
ABO
0.720 GeneticVariation BEFREE We selected four single nucleotide polymorphisms (rs579459, rs651007, rs514659 and rs529565) of the ABO gene and performed genotyping assays to assess the association with ischemic stroke and its subtypes. 27542834

2016

dbSNP: rs529565
rs529565
ABO
C 0.720 GeneticVariation GWASCAT Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis. 26908601

2016

dbSNP: rs1799963
rs1799963
F2
0.720 GeneticVariation BEFREE We evaluated the differences in the distribution of rs6025 and rs1799963 polymorphisms according to IS subtypes and their interaction with smoking. 25897999

2015

dbSNP: rs10744777
rs10744777
0.720 GeneticVariation BEFREE In an overall analysis of 17,970 cases of ischemic stroke and 70,764 controls, we identified a novel association on chromosome 12q24 (rs10744777, odds ratio [OR] 1.10 [1.07-1.13], p = 7.12 × 10(-11)) with ischemic stroke. 25031287

2014

dbSNP: rs505922
rs505922
ABO
0.720 GeneticVariation BEFREE SNP rs505922 was nominally associated with ischemic stroke (odds ratio = 0.94, 95% confidence interval = 0.88-0.99, p = 0.023). 23381943

2013

dbSNP: rs2107595
rs2107595
0.710 GeneticVariation GWASCAT Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354

2018

dbSNP: rs11196288
rs11196288
0.710 GeneticVariation BEFREE The results indicated that the role of rs11196288 polymorphism in ischemic stroke susceptibility in Chinese Han population may be different from that in European. 28501930

2017

dbSNP: rs11196288
rs11196288
G 0.710 GeneticVariation GWASCAT Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2. 26732560

2016

dbSNP: rs2107595
rs2107595
A 0.710 GeneticVariation GWASCAT Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. 26708676

2016