Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs55770810
rs55770810
A 0.800 CausalMutation CLINVAR

dbSNP: rs1064795649
rs1064795649
T 0.700 CausalMutation CLINVAR

dbSNP: rs118203998
rs118203998
C 0.700 CausalMutation CLINVAR

dbSNP: rs137852986
rs137852986
A 0.700 CausalMutation CLINVAR

dbSNP: rs138213197
rs138213197
T 0.700 CausalMutation CLINVAR

dbSNP: rs34612342
rs34612342
C 0.700 CausalMutation CLINVAR

dbSNP: rs587776650
rs587776650
NBN
A 0.700 CausalMutation CLINVAR

dbSNP: rs587781803
rs587781803
A 0.700 CausalMutation CLINVAR

dbSNP: rs63750695
rs63750695
C 0.700 CausalMutation CLINVAR

dbSNP: rs80356898
rs80356898
A 0.700 CausalMutation CLINVAR

dbSNP: rs80357233
rs80357233
C 0.700 CausalMutation CLINVAR

dbSNP: rs80357438
rs80357438
T 0.700 CausalMutation CLINVAR

dbSNP: rs80357669
rs80357669
T 0.700 CausalMutation CLINVAR

dbSNP: rs80357828
rs80357828
G 0.700 CausalMutation CLINVAR

dbSNP: rs80358981
rs80358981
T 0.700 CausalMutation CLINVAR

dbSNP: rs80359477
rs80359477
G 0.700 CausalMutation CLINVAR

dbSNP: rs869312774
rs869312774
C 0.700 CausalMutation CLINVAR

dbSNP: rs1801155
rs1801155
APC
A 0.720 SusceptibilityMutation CLINVAR

dbSNP: rs55770810
rs55770810
0.800 GeneticVariation UNIPROT

dbSNP: rs28897672
rs28897672
0.730 GeneticVariation BEFREE The risk for breast cancer was 42% higher among first degree relatives of carriers of the C61G missense mutation compared to other mutations (HR = 1.42; p = 0.10) and the risk for ovarian cancer was lower than average (OR = 0.26; p = 0.03). 16227521

2006

dbSNP: rs28897672
rs28897672
0.730 GeneticVariation UNIPROT

dbSNP: rs28897672
rs28897672
0.730 GeneticVariation BEFREE We identified a founder mutation (4153delA, 5382insC or C61G) in 6% of 235 unselected cases of breast cancer and in 19% of 43 unselected cases of ovarian cancer. 20345474

2010

dbSNP: rs28897672
rs28897672
0.730 GeneticVariation BEFREE While the Cys61Gly mutation appeared underrepresented in ovarian cancer as compared with breast cancer cases from the same population (p = 0.01), the 4153delA mutation made a higher contribution to ovarian cancer than to breast cancer (p < 0.01). 20569256

2010

dbSNP: rs1801155
rs1801155
APC
0.720 GeneticVariation BEFREE To determine whether the excess of colon cancer in some breast-ovarian cancer families is related to the I1307K mutation, we evaluated 264 Ashkenazi Jews from 158 families. 9407954

1997

dbSNP: rs1801155
rs1801155
APC
0.720 GeneticVariation BEFREE In the Ashkenazi Jewish population, the I1307K allele is unlikely to increase the risk of ovarian cancer or of cancer in general. 9679945

1998