Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3814113
rs3814113
0.720 GeneticVariation GWASDB GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. 23535730

2013

dbSNP: rs3814113
rs3814113
T 0.720 GeneticVariation GWASDB The most significant SNP (rs3814113; P = 2.5 x 10(-17)) was genotyped in a further 2,670 ovarian cancer cases and 4,668 controls, confirming its association (combined data odds ratio (OR) = 0.82, 95% confidence interval (CI) 0.79-0.86, P(trend) = 5.1 x 10(-19)). 19648919

2009

dbSNP: rs3814113
rs3814113
0.720 GeneticVariation BEFREE A genome-wide association study recently identified an association between the rare allele of the single-nucleotide polymorphism (SNP) rs3814113 (ie, the C allele) at 9p22.2 and decreased risk of ovarian cancer for women in the general population. 21169536

2011

dbSNP: rs3814113
rs3814113
0.720 GeneticVariation BEFREE To assess the potential implications of microRNAs in ovarian cancer, we investigated the associations between microRNA expression and seven ovarian cancer risk variants discovered from genome-wide association studies (GWAS), namely, rs3814113 on 9p22.2, rs2072590 on 2q31, rs2665390 on 3q25, rs10088218, rs1516982, rs10098821 on 8q24.21 and rs2363956 on 19p13. 22235027

2012

dbSNP: rs10810666
rs10810666
0.700 GeneticVariation GWASDB A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. 19648919

2009

dbSNP: rs10962656
rs10962656
0.700 GeneticVariation GWASDB A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. 19648919

2009

dbSNP: rs4445329
rs4445329
0.700 GeneticVariation GWASDB A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. 19648919

2009

dbSNP: rs2660753
rs2660753
0.020 GeneticVariation BEFREE SNP rs2660753 (chromosome 3p12) showed evidence of association with ovarian cancer [per minor allele OR, 1.19; 95% confidence interval (95% CI), 1.04-1.37; P(trend) = 0.012]. 18974127

2008

dbSNP: rs2660753
rs2660753
0.020 GeneticVariation BEFREE Prostate cancer susceptibility polymorphism rs2660753 is not associated with invasive ovarian cancer. 21415361

2011

dbSNP: rs1024611
rs1024611
0.010 GeneticVariation BEFREE These data suggest that MCP-1 rs1024611A/G and rs3760396C/G polymorphisms are associated with increased susceptibility to ovarian cancer, in which rs1024611A/G may increase serum level of MCP-1 in the Chinese population. 25289731

2015

dbSNP: rs4954956
rs4954956
0.010 GeneticVariation BEFREE In conclusion, we found that rs4954956 was associated with increased ovarian cancer risk, particularly for serous ovarian cancer. 19304784

2009

dbSNP: rs67397200
rs67397200
0.010 GeneticVariation BEFREE We also found for the first time that rs67397200 at 19p13.1 was associated with an increased risk of ovarian cancer for BRCA1 (HR, 1.16; 95% CI, 1.05-1.29; P = 3.8 × 10(-4)) and BRCA2 mutation carriers (HR, 1.30; 95% CI, 1.10-1.52; P = 1.8 × 10(-3)). 22351618

2012

dbSNP: rs6785617
rs6785617
0.010 GeneticVariation BEFREE Considering a multiple-testing-corrected significance threshold of P < 2.5 × 10(-5), only one other variant, the TNFSF10 SNP rs6785617, was associated significantly with a risk of ovarian cancer (low malignant potential tumors OR, 0.85; 95% CI, 0.79-0.91; P = 0.00002). 24272484

2014

dbSNP: rs7313833
rs7313833
0.010 GeneticVariation BEFREE Initially, three SNPs (rs2107425 in MRPL23, rs7313833 in PTHLH, rs3803662 in TNRC9) were weakly associated with ovarian cancer risk and one SNP (rs4954956 in NXPH2) was associated with serous ovarian cancer in non-Hispanic white subjects (P-trend < 0.1). 19304784

2009

dbSNP: rs7365052
rs7365052
0.010 GeneticVariation BEFREE Two SNPs (rs7365052, rs7526063) showed borderline significant inverse associations with ovarian cancer risk; both had very low minor allele frequencies. 21629268

2011

dbSNP: rs874945
rs874945
0.010 GeneticVariation BEFREE SNPs rs12826786, rs7958904, and rs874945 did not correlate with an effect on patient susceptibility to BC, CC, and OC. 30484890

2018

dbSNP: rs2032582
rs2032582
0.010 GeneticVariation BEFREE The mdr-1 polymorphism G2677T/A in exon 21 correlates with the paclitaxel response in ovarian cancer and may be important for the function of P-glycoprotein and resistance to paclitaxel and provide useful information for individualized therapy. 16467099

2006

dbSNP: rs2229109
rs2229109
0.010 GeneticVariation BEFREE ABCB1 G1199A polymorphism and ovarian cancer response to paclitaxel. 17828752

2008

dbSNP: rs35068177
rs35068177
0.010 GeneticVariation BEFREE The SNPs C1236T, G1199T/A, and A1308G were determined using Pyrosequencing in 51 patients with advanced ovarian cancer and correlated to the progression free survival. 17828752

2008

dbSNP: rs186724
rs186724
0.010 GeneticVariation BEFREE Firstly, individuals carried ERBB4 rs186724 GG genotype had poorer overall survival compared with those carried CC/CT genotypes in ovarian cancer, while the participants with rs1836724 GA genotype had the same overall survival with that in participants with rs1836724 AA genotype in accordance with the result of Cox regression and Kaplan-Meier analyses. 29125883

2018

dbSNP: rs121434592
rs121434592
0.030 GeneticVariation BEFREE They described a novel point mutation (E17K) in the pleckstrin homology domain (PHD) of the AKT1 gene in human breast, colorectal and ovarian cancers, and demonstrated that it induces leukemia in mice. 17921701

2007

dbSNP: rs121434592
rs121434592
0.030 GeneticVariation BEFREE An earlier study discovered an oncogenic AKT1 gene mutation (AKT1 E17K) in breast, colorectal and ovarian cancers. 18392055

2008

dbSNP: rs121434592
rs121434592
0.030 GeneticVariation BEFREE Recently, a somatic mutation in AKT1 (E17K) has been detected in breast, colorectal, lung and ovarian cancers. 18504432

2008

dbSNP: rs387906659
rs387906659
0.020 GeneticVariation BEFREE They described a novel point mutation (E17K) in the pleckstrin homology domain (PHD) of the AKT1 gene in human breast, colorectal and ovarian cancers, and demonstrated that it induces leukemia in mice. 17921701

2007

dbSNP: rs387906659
rs387906659
0.020 GeneticVariation BEFREE An earlier study discovered an oncogenic AKT1 gene mutation (AKT1 E17K) in breast, colorectal and ovarian cancers. 18392055

2008