Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs55770810
rs55770810
0.800 GeneticVariation UNIPROT

dbSNP: rs28897672
rs28897672
0.730 GeneticVariation BEFREE The risk for breast cancer was 42% higher among first degree relatives of carriers of the C61G missense mutation compared to other mutations (HR = 1.42; p = 0.10) and the risk for ovarian cancer was lower than average (OR = 0.26; p = 0.03). 16227521

2006

dbSNP: rs28897672
rs28897672
0.730 GeneticVariation UNIPROT

dbSNP: rs28897672
rs28897672
0.730 GeneticVariation BEFREE We identified a founder mutation (4153delA, 5382insC or C61G) in 6% of 235 unselected cases of breast cancer and in 19% of 43 unselected cases of ovarian cancer. 20345474

2010

dbSNP: rs28897672
rs28897672
0.730 GeneticVariation BEFREE While the Cys61Gly mutation appeared underrepresented in ovarian cancer as compared with breast cancer cases from the same population (p = 0.01), the 4153delA mutation made a higher contribution to ovarian cancer than to breast cancer (p < 0.01). 20569256

2010

dbSNP: rs1801155
rs1801155
APC
0.720 GeneticVariation BEFREE To determine whether the excess of colon cancer in some breast-ovarian cancer families is related to the I1307K mutation, we evaluated 264 Ashkenazi Jews from 158 families. 9407954

1997

dbSNP: rs1801155
rs1801155
APC
0.720 GeneticVariation BEFREE In the Ashkenazi Jewish population, the I1307K allele is unlikely to increase the risk of ovarian cancer or of cancer in general. 9679945

1998

dbSNP: rs2072590
rs2072590
0.720 GeneticVariation GWASDB GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. 23535730

2013

dbSNP: rs2072590
rs2072590
0.720 GeneticVariation BEFREE To assess the potential implications of microRNAs in ovarian cancer, we investigated the associations between microRNA expression and seven ovarian cancer risk variants discovered from genome-wide association studies (GWAS), namely, rs3814113 on 9p22.2, rs2072590 on 2q31, rs2665390 on 3q25, rs10088218, rs1516982, rs10098821 on 8q24.21 and rs2363956 on 19p13. 22235027

2012

dbSNP: rs2072590
rs2072590
0.720 GeneticVariation BEFREE The OC risk-associated SNP rs2072590 lies in non-coding DNA downstream of <i>HOXD3</i> and upstream of <i>HOXD1</i>, and it tags SNPs in the <i>HOXD3</i> 3' UTR. 29262571

2017

dbSNP: rs3814113
rs3814113
0.720 GeneticVariation BEFREE To assess the potential implications of microRNAs in ovarian cancer, we investigated the associations between microRNA expression and seven ovarian cancer risk variants discovered from genome-wide association studies (GWAS), namely, rs3814113 on 9p22.2, rs2072590 on 2q31, rs2665390 on 3q25, rs10088218, rs1516982, rs10098821 on 8q24.21 and rs2363956 on 19p13. 22235027

2012

dbSNP: rs3814113
rs3814113
0.720 GeneticVariation BEFREE A genome-wide association study recently identified an association between the rare allele of the single-nucleotide polymorphism (SNP) rs3814113 (ie, the C allele) at 9p22.2 and decreased risk of ovarian cancer for women in the general population. 21169536

2011

dbSNP: rs3814113
rs3814113
0.720 GeneticVariation GWASDB GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. 23535730

2013

dbSNP: rs10088218
rs10088218
0.710 GeneticVariation GWASDB GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. 23535730

2013

dbSNP: rs10088218
rs10088218
0.710 GeneticVariation BEFREE To assess the potential implications of microRNAs in ovarian cancer, we investigated the associations between microRNA expression and seven ovarian cancer risk variants discovered from genome-wide association studies (GWAS), namely, rs3814113 on 9p22.2, rs2072590 on 2q31, rs2665390 on 3q25, rs10088218, rs1516982, rs10098821 on 8q24.21 and rs2363956 on 19p13. 22235027

2012

dbSNP: rs121913279
rs121913279
0.710 GeneticVariation BEFREE We also found that an activating (E545K) Pik3ca mutation, unlike Pten inactivation or Pik3ca H1047R mutation, cannot cooperate with Arid1a loss to promote ovarian cancer development in the mouse. 26279473

2016

dbSNP: rs121913279
rs121913279
0.710 GeneticVariation UNIPROT Mutation of the PIK3CA gene in ovarian and breast cancer. 15520168

2004

dbSNP: rs17879961
rs17879961
0.710 GeneticVariation BEFREE The association between the I157T missense variant was then confirmed in a second sample of Russian patients with borderline ovarian cancers</span> (OR = 2.7; P = 0.06). 16828850

2006

dbSNP: rs2363956
rs2363956
0.710 GeneticVariation BEFREE To assess the potential implications of microRNAs in ovarian cancer, we investigated the associations between microRNA expression and seven ovarian cancer risk variants discovered from genome-wide association studies (GWAS), namely, rs3814113 on 9p22.2, rs2072590 on 2q31, rs2665390 on 3q25, rs10088218, rs1516982, rs10098821 on 8q24.21 and rs2363956 on 19p13. 22235027

2012

dbSNP: rs2665390
rs2665390
0.710 GeneticVariation BEFREE To assess the potential implications of microRNAs in ovarian cancer, we investigated the associations between microRNA expression and seven ovarian cancer risk variants discovered from genome-wide association studies (GWAS), namely, rs3814113 on 9p22.2, rs2072590 on 2q31, rs2665390 on 3q25, rs10088218, rs1516982, rs10098821 on 8q24.21 and rs2363956 on 19p13. 22235027

2012

dbSNP: rs10756819
rs10756819
0.700 GeneticVariation GWASDB A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. 19648919

2009

dbSNP: rs10810666
rs10810666
0.700 GeneticVariation GWASDB A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. 19648919

2009

dbSNP: rs10962656
rs10962656
0.700 GeneticVariation GWASDB A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. 19648919

2009

dbSNP: rs113954997
rs113954997
0.700 GeneticVariation UNIPROT

dbSNP: rs1199923024
rs1199923024
0.700 GeneticVariation UNIPROT