Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17568
rs17568
0.010 GeneticVariation BEFREE Association of OX40 gene polymorphisms (rs17568G/A and rs229811A/C) with head and neck squamous cell carcinoma. 30923998

2019

dbSNP: rs229811
rs229811
0.010 GeneticVariation BEFREE Association of OX40 gene polymorphisms (rs17568G/A and rs229811A/C) with head and neck squamous cell carcinoma. 30923998

2019

dbSNP: rs11016879
rs11016879
0.010 GeneticVariation BEFREE The MGMT rs11016879 AG genotype and A allele were associated with increased HNSCC risk. 29370316

2018

dbSNP: rs12917
rs12917
0.010 GeneticVariation BEFREE Our results indicated that the MGMT rs12917 TT genotype increases the risk of HNSCC. 29370316

2018

dbSNP: rs2273535
rs2273535
0.010 GeneticVariation BEFREE The Aurora-Kinase A Phe31-Ile polymorphism as possible predictor of response to treatment in head and neck squamous cell carcinoma. 29560108

2018

dbSNP: rs26537
rs26537
0.010 GeneticVariation BEFREE Finally, we identified that rs26537 of ATG12 (additive model: adjusted odds ratio [OR] = 1.19, 95% confidence interval [CI] = 1.03-1.37, P = 0.017) and rs4663402 in ATG16L1 (additive model: adjusted OR = 1.39, 95%CI = 1.08-1.80, P = 0.010) were significantly associated with the increased risk of HNSCC. 29637616

2018

dbSNP: rs4663402
rs4663402
0.010 GeneticVariation BEFREE Finally, we identified that rs26537 of ATG12 (additive model: adjusted odds ratio [OR] = 1.19, 95% confidence interval [CI] = 1.03-1.37, P = 0.017) and rs4663402 in ATG16L1 (additive model: adjusted OR = 1.39, 95%CI = 1.08-1.80, P = 0.010) were significantly associated with the increased risk of HNSCC. 29637616

2018

dbSNP: rs4759314
rs4759314
0.010 GeneticVariation BEFREE HOTAIR rs4759314 may influence HNSCC susceptibility and serve as a diagnostic biomarker. 29461598

2018

dbSNP: rs7958904
rs7958904
0.010 GeneticVariation BEFREE However, there were no significant associations of rs874945 and rs7958904 with HNSCC risk. 29461598

2018

dbSNP: rs874945
rs874945
0.010 GeneticVariation BEFREE However, there were no significant associations of rs874945 and rs7958904 with HNSCC risk. 29461598

2018

dbSNP: rs9350
rs9350
0.010 GeneticVariation BEFREE This prospective study aimed to investigate whether <i>MLH1</i> c.-93G>A (rs1800734), <i>MSH2</i> c.211+9C>G (rs2303426), <i>MSH3</i> c.3133G>A (rs26279), <i>EXO1</i> c.1765G>A (rs1047840), and <i>EXO1</i> c.2270C>T (rs9350) single nucleotide polymorphisms (SNPs) of the mismatch repair (MMR) pathway change side effects and response rate of 90 HNSCC patients treated with CDDP and RT. 30038702

2018

dbSNP: rs1034220998
rs1034220998
0.010 GeneticVariation BEFREE This study aimed to investigate the associations of XPC c.2815A>C, XPD c.934G>A and c.2251A>C, XPF c.2505T>C and ERCC1 c.354C>T single nucleotide polymorphisms (SNPs) of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma (HNSCC) patients treated with cisplatin (CDDP) chemoradiation. 26918827

2017

dbSNP: rs11615
rs11615
0.010 GeneticVariation BEFREE This study aimed to investigate the associations of XPC c.2815A>C, XPD c.934G>A and c.2251A>C, XPF c.2505T>C and ERCC1 c.354C>T single nucleotide polymorphisms (SNPs) of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma (HNSCC) patients treated with cisplatin (CDDP) chemoradiation. 26918827

2017

dbSNP: rs121434569
rs121434569
0.010 GeneticVariation BEFREE Higher frequency of EGFR-TK domain mutations together with the presence of the T790M mutation suggests that identification of these mutations might streamline the therapy and provide a better prognosis in HNSCC cases. 28352186

2017

dbSNP: rs1256743514
rs1256743514
0.010 GeneticVariation BEFREE The mutational analysis in the eight HNSCC cell lines revealed an <i>EGFR</i> mutation (p.H773Y) and gene amplification in the HN13 cells. 28881811

2017

dbSNP: rs17084687
rs17084687
KIT
0.010 GeneticVariation BEFREE Furthermore, interaction analyses revealed a significant multiplicative interaction between rs17084687 and drinking on HNSCC risk (P = 0.012). 27186940

2017

dbSNP: rs1799793
rs1799793
0.010 GeneticVariation BEFREE XPD c.934G>A polymorphism of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation. 26918827

2017

dbSNP: rs1799801
rs1799801
0.010 GeneticVariation BEFREE This study aimed to investigate the associations of XPC c.2815A>C, XPD c.934G>A and c.2251A>C, XPF c.2505T>C and ERCC1 c.354C>T single nucleotide polymorphisms (SNPs) of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma (HNSCC) patients treated with cisplatin (CDDP) chemoradiation. 26918827

2017

dbSNP: rs2237025
rs2237025
KIT
0.010 GeneticVariation BEFREE Logistic regression analyses revealed that an upstream SNP rs6554198 [additive model: adjusted odds ratio (OR) = 0.85, 95% confidence interval (CI) = 0.74-0.97, P = 0.019] and two intron SNPs rs2237025 (additive model: adjusted OR = 0.82, 95%CI = 0.70-0.95, P = 0.007), and rs17084687 (additive model: adjusted OR = 0.85, 95%CI = 0.73-0.99, P = 0.042) of KIT were significantly associated with the decreased risk of HNSCC. 27186940

2017

dbSNP: rs2280148
rs2280148
0.010 GeneticVariation BEFREE We found that rs2280148 located at 3'-untranslated region of SOCS3 was significantly associated with an increased risk of HNSCC (additive model: adjusted OR = 1.21, 95% CI = 1.03-1.43, P = 0.021). 27977878

2017

dbSNP: rs368731455
rs368731455
0.010 GeneticVariation BEFREE XPD c.934G>A polymorphism of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation. 26918827

2017

dbSNP: rs371194629
rs371194629
0.010 GeneticVariation BEFREE The HLA-G polymorphism at 3'UTR 14bp INDEL (rs371194629) and +3142G/C (rs1063320) were studied in 383 HNSCC patients and 383 ethnically similar-aged healthy controls in North Indian population. 28040535

2017

dbSNP: rs6554198
rs6554198
KIT
0.010 GeneticVariation BEFREE Logistic regression analyses revealed that an upstream SNP rs6554198 [additive model: adjusted odds ratio (OR) = 0.85, 95% confidence interval (CI) = 0.74-0.97, P = 0.019] and two intron SNPs rs2237025 (additive model: adjusted OR = 0.82, 95%CI = 0.70-0.95, P = 0.007), and rs17084687 (additive model: adjusted OR = 0.85, 95%CI = 0.73-0.99, P = 0.042) of KIT were significantly associated with the decreased risk of HNSCC. 27186940

2017

dbSNP: rs757503234
rs757503234
XPC
0.010 GeneticVariation BEFREE XPD c.934G>A polymorphism of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma patients treated with cisplatin chemoradiation. 26918827

2017

dbSNP: rs758821654
rs758821654
0.010 GeneticVariation BEFREE This study aimed to investigate the associations of XPC c.2815A>C, XPD c.934G>A and c.2251A>C, XPF c.2505T>C and ERCC1 c.354C>T single nucleotide polymorphisms (SNPs) of nucleotide excision repair pathway in outcome of head and neck squamous cell carcinoma (HNSCC) patients treated with cisplatin (CDDP) chemoradiation. 26918827

2017