Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121909237
rs121909237
PTEN
G 0.800 CausalMutation CLINVAR

dbSNP: rs1064793881
rs1064793881
TP53
T 0.700 GeneticVariation CLINVAR

dbSNP: rs121909250
rs121909250
ING1
C 0.700 CausalMutation CLINVAR

dbSNP: rs121909251
rs121909251
ING1
G 0.700 CausalMutation CLINVAR

dbSNP: rs121909252
rs121909252
ING1
A 0.700 CausalMutation CLINVAR

dbSNP: rs121912664
rs121912664
TP53
T 0.700 CausalMutation CLINVAR

dbSNP: rs1567549584
rs1567549584
TP53
C 0.700 GeneticVariation CLINVAR

dbSNP: rs201613442
rs201613442
TNNI3K ; FPGT-TNNI3K ; LRRC53
0.700 GeneticVariation UNIPROT

dbSNP: rs397514495
rs397514495
TP53
T 0.700 GeneticVariation CLINVAR

dbSNP: rs587782144
rs587782144
TP53
G 0.700 GeneticVariation CLINVAR

dbSNP: rs25487
rs25487
XRCC1
0.050 GeneticVariation BEFREE Arg399Gln of XRCC1 appears to have a protective role in people those consume alcohol, while XPD Lys751Gln variants indicated ∼2-fold increased risk of SCCHN in all the co-variate groups. 21945240

2012
dbSNP: rs759412116
rs759412116
ERCC2
0.010 GeneticVariation BEFREE Arg399Gln of XRCC1 appears to have a protective role in people those consume alcohol, while XPD Lys751Gln variants indicated ∼2-fold increased risk of SCCHN in all the co-variate groups. 21945240

2012
dbSNP: rs1052133
rs1052133
OGG1 ; CAMK1
0.040 GeneticVariation BEFREE Our results demonstrate that Ser326Cys variant genotype is associated with an increased risk of SCCHN in north India. 21986195

2011
dbSNP: rs1229984
rs1229984
ADH1B
0.030 GeneticVariation BEFREE ADH1B histidine allele (rs1229984), CYP2E1 rs3813867 heterozygous genotype, and GSTT1 deletion conferred protection against HNSCC (OR: 0.318 [0.04-0.75], OR: 0.13 [0.02-0.94], and OR: 0.12 [0.02-0.60], respectively) while GSTP1 (rs1695) Val/Val genotype was related to an increased risk (OR: 4.12 [1.11-15.31]). 25639971

2015
dbSNP: rs3813867
rs3813867
CYP2E1 ; LOC107984284
0.010 GeneticVariation BEFREE ADH1B histidine allele (rs1229984), CYP2E1 rs3813867 heterozygous genotype, and GSTT1 deletion conferred protection against HNSCC (OR: 0.318 [0.04-0.75], OR: 0.13 [0.02-0.94], and OR: 0.12 [0.02-0.60], respectively) while GSTP1 (rs1695) Val/Val genotype was related to an increased risk (OR: 4.12 [1.11-15.31]). 25639971

2015
dbSNP: rs1695
rs1695
GSTP1
0.050 GeneticVariation BEFREE ADH1B histidine allele (rs1229984), CYP2E1 rs3813867 heterozygous genotype, and GSTT1 deletion conferred protection against HNSCC (OR: 0.318 [0.04-0.75], OR: 0.13 [0.02-0.94], and OR: 0.12 [0.02-0.60], respectively) while GSTP1 (rs1695) Val/Val genotype was related to an increased risk (OR: 4.12 [1.11-15.31]). 25639971

2015
dbSNP: rs3213182
rs3213182
E2F1 ; NECAB3
0.010 GeneticVariation BEFREE Although none of the selected SNPs alone was significantly associated with risk of SCCHN, there was a statistically significantly increased risk of SCCHN associated with the combined risk genotypes (i.e., rs3213182 AA, rs3213183 GG, rs3213180 GG, rs321318121 GG, rs2742976 GT+TT, rs6667575 GA+AA, rs3218203 CC, rs3218148 AA, rs3218211 CC, and rs3218123 GT+TT). 22344756

2012
dbSNP: rs3213183
rs3213183
E2F1 ; NECAB3
0.010 GeneticVariation BEFREE Although none of the selected SNPs alone was significantly associated with risk of SCCHN, there was a statistically significantly increased risk of SCCHN associated with the combined risk genotypes (i.e., rs3213182 AA, rs3213183 GG, rs3213180 GG, rs321318121 GG, rs2742976 GT+TT, rs6667575 GA+AA, rs3218203 CC, rs3218148 AA, rs3218211 CC, and rs3218123 GT+TT). 22344756

2012
dbSNP: rs3213180
rs3213180
E2F1 ; NECAB3
0.010 GeneticVariation BEFREE Although none of the selected SNPs alone was significantly associated with risk of SCCHN, there was a statistically significantly increased risk of SCCHN associated with the combined risk genotypes (i.e., rs3213182 AA, rs3213183 GG, rs3213180 GG, rs321318121 GG, rs2742976 GT+TT, rs6667575 GA+AA, rs3218203 CC, rs3218148 AA, rs3218211 CC, and rs3218123 GT+TT). 22344756

2012
dbSNP: rs2742976
rs2742976
E2F2
0.010 GeneticVariation BEFREE Although none of the selected SNPs alone was significantly associated with risk of SCCHN, there was a statistically significantly increased risk of SCCHN associated with the combined risk genotypes (i.e., rs3213182 AA, rs3213183 GG, rs3213180 GG, rs321318121 GG, rs2742976 GT+TT, rs6667575 GA+AA, rs3218203 CC, rs3218148 AA, rs3218211 CC, and rs3218123 GT+TT). 22344756

2012
dbSNP: rs3218123
rs3218123
E2F2
0.010 GeneticVariation BEFREE Although none of the selected SNPs alone was significantly associated with risk of SCCHN, there was a statistically significantly increased risk of SCCHN associated with the combined risk genotypes (i.e., rs3213182 AA, rs3213183 GG, rs3213180 GG, rs321318121 GG, rs2742976 GT+TT, rs6667575 GA+AA, rs3218203 CC, rs3218148 AA, rs3218211 CC, and rs3218123 GT+TT). 22344756

2012
dbSNP: rs3218148
rs3218148
E2F2 ; LOC101928163
0.010 GeneticVariation BEFREE Although none of the selected SNPs alone was significantly associated with risk of SCCHN, there was a statistically significantly increased risk of SCCHN associated with the combined risk genotypes (i.e., rs3213182 AA, rs3213183 GG, rs3213180 GG, rs321318121 GG, rs2742976 GT+TT, rs6667575 GA+AA, rs3218203 CC, rs3218148 AA, rs3218211 CC, and rs3218123 GT+TT). 22344756

2012
dbSNP: rs3218203
rs3218203
E2F2
0.010 GeneticVariation BEFREE Although none of the selected SNPs alone was significantly associated with risk of SCCHN, there was a statistically significantly increased risk of SCCHN associated with the combined risk genotypes (i.e., rs3213182 AA, rs3213183 GG, rs3213180 GG, rs321318121 GG, rs2742976 GT+TT, rs6667575 GA+AA, rs3218203 CC, rs3218148 AA, rs3218211 CC, and rs3218123 GT+TT). 22344756

2012
dbSNP: rs3218211
rs3218211
E2F2
0.010 GeneticVariation BEFREE Although none of the selected SNPs alone was significantly associated with risk of SCCHN, there was a statistically significantly increased risk of SCCHN associated with the combined risk genotypes (i.e., rs3213182 AA, rs3213183 GG, rs3213180 GG, rs321318121 GG, rs2742976 GT+TT, rs6667575 GA+AA, rs3218203 CC, rs3218148 AA, rs3218211 CC, and rs3218123 GT+TT). 22344756

2012
dbSNP: rs6667575
rs6667575
E2F2
0.010 GeneticVariation BEFREE Although none of the selected SNPs alone was significantly associated with risk of SCCHN, there was a statistically significantly increased risk of SCCHN associated with the combined risk genotypes (i.e., rs3213182 AA, rs3213183 GG, rs3213180 GG, rs321318121 GG, rs2742976 GT+TT, rs6667575 GA+AA, rs3218203 CC, rs3218148 AA, rs3218211 CC, and rs3218123 GT+TT). 22344756

2012