DisGeNET - a database of gene-disease associations

Attention deficit hyperactivity disorder, C1263846

Variant: rs6551665 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs6551665

ADGRL3

0.030

GeneticVariation

BEFREE

We tested the association of an ADGRL3 variant (rs6551665</span>) with both early-onset ADHD and ASD susceptibility.

30652248

2019

dbSNP:

rs6551665

ADGRL3

0.030

GeneticVariation

BEFREE

In the group composed by predominantly hyperactive/impulsive and combined presentation, the presence of LPHN3-rs6551665 G allele was related to increased ADHD risk only in individuals carrying the TTC12-rs2303380 AA genotype (p=0.026).

28624582

2017

dbSNP:

rs6551665

ADGRL3

0.030

GeneticVariation

BEFREE

Thus our results imply that the LPHN3 rs6551665 GG genotype and G allele may provide a significant effect on the ADHD, although larger sample sizes and functional studies are necessary to further elucidate these findings.

25871512

2015