Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2230912
rs2230912
0.070 GeneticVariation BEFREE We found a significant association between rs2230912 and combined mood disorders (major depressive disorder (MDD) or bipolar disorder (BD)) for the allelic, dominant and heterozygous-disadvantage model, all withstanding the threshold of correction for multiple testing. 29122639

2018

dbSNP: rs2230912
rs2230912
0.070 GeneticVariation BEFREE To investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV. 23157339

2013

dbSNP: rs2230912
rs2230912
0.070 GeneticVariation BEFREE The results suggest that P2RX7 gene polymorphisms Gln460Arg</span> (rs2230912) and His155Tyr (rs208294) are not associated with MDD or remission after SSRI or ECT. 21335057

2011

dbSNP: rs2230912
rs2230912
0.070 GeneticVariation BEFREE The single nucleotide polymorphisms FKBP5:rs1360780, BDNF:rs6265 (Val66Met), P2RX7:2230912 (Gln460Arg) and CACNA1C:rs1006737 were genotyped in DNA from 457 depression cases (major depression, dysthymia, and mixed anxiety depression) and 2286 healthy controls with no symptom of psychopathology. 20226536

2010

dbSNP: rs2230912
rs2230912
0.070 GeneticVariation BEFREE We found no allelic or genotypic association between rs2230912 and BPI or Mdd-UP both in the national samples and in the combined European patient sample. 19330776

2009

dbSNP: rs2230912
rs2230912
0.070 GeneticVariation BEFREE Here we present a case-control analysis of 171 patients diagnosed with MDD or BPD and 178 controls, as well as a dimensional approach using the Hospital Anxiety and Depression Scale (HADS) for studying the Gln460Arg polymorphism of the P2RX7 gene as a genetic risk factor in depression. 18543274

2009

dbSNP: rs2230912
rs2230912
0.070 GeneticVariation BEFREE A non-synonymous coding SNP in the P2RX7 gene (rs2230912), previously found to be associated with bipolar disorder, was significantly associated (P=0.0019) with MDD. 16822851

2006