Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2242446
rs2242446
SLC6A2
0.060 GeneticVariation BEFREE A functional NET T-182C polymorphism (rs2242446) in the promoter region and a synonymous polymorphisms G1287A in the exon 9 (rs5569) were associated with MDD in different populations. 29703117

2018
dbSNP: rs2242446
rs2242446
SLC6A2
0.060 GeneticVariation BEFREE Overall analysis and subgroup analysis indicated no significant association between NET gene rs2242446 polymorphism and MDD risk. 30292339

2018
dbSNP: rs2242446
rs2242446
SLC6A2
0.060 GeneticVariation BEFREE NET rs2242446/T-182C may serve as a biomarker to predict the likelihood of remission with venlafaxine in older adults with major depression. 28068779

2017
dbSNP: rs2242446
rs2242446
SLC6A2
0.060 GeneticVariation BEFREE We investigated the separate effects and possible interactions between NET T-182C (rs2242446) and SERT 5-HTTLPR (rs4795541) polymorphisms on selective serotonin reuptake inhibitors (SSRI) treatment response and temperamental traits assessed by the Temperament and Character Inventory (TCI) in a clinical sample of subjects with major depressive disorder (MDD). 25739526

2015
dbSNP: rs2242446
rs2242446
SLC6A2
0.060 GeneticVariation BEFREE In this study, we examined whether rs2242446 and rs5569 genetic variants are related to the etiology of MDD using a meta-analysis. 23648227

2013
dbSNP: rs2242446
rs2242446
SLC6A2
0.060 GeneticVariation BEFREE The present study suggests that the combined effect of rs2242446 and rs5569 in the NET gene could modify the response to the negative life events in triggering MD. 18779921

2008