Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE <i>MTHFR</i> A1298C is implicated in irregular homocysteine metabolism and aberrant folate cycles and, through this, it may play a role as either a driver in the development of MDD or as a predictive or diagnostic marker, possibly in combination with C677T. 29209581

2017
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE 330 adult patients with MDD (DSM-5) and positive for either MTHFR C677T or A1298C polymorphism were enrolled in a trial conducted between August 1, 2014, and April 3, 2015. 27035272

2016
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE This study showed the involvement of A1298C, Val158Met and their interaction in MDD. 26021967

2015
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE Neither the A1298C polymorphism nor any of the htSNPs were associated with MDD prognosis regardless of measure used. 24123968

2014
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE This study shows that CC genotype of the MTHFR A1298C is associated with higher risk of MDD in Slovak population. 23255668

2012