Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs759834365
rs759834365
0.060 GeneticVariation BEFREE Impact of APOE and BDNF Val66Met Gene Polymorphisms on Cognitive Functions in Patients with Amnestic Mild Cognitive Impairment. 31771052

2020

dbSNP: rs759834365
rs759834365
0.060 GeneticVariation BEFREE A total of 1,081 adults without dementia (375 healthy subjects and 706 individuals with mild cognitive impairment) were recruited from the Alzheimer's Disease Neuroimaging Initiative (ADNI) to test the influence of BDNF Val66Met polymorphism on cognitive impairment, brain structure atrophy, and change in the levels of CSF biomarkers. 30775992

2019

dbSNP: rs759834365
rs759834365
0.060 GeneticVariation BEFREE Physical exercise improves peripheral BDNF levels and cognitive functions in mild cognitive impairment elderly with different bdnf Val66Met genotypes. 25062900

2015

dbSNP: rs759834365
rs759834365
0.060 GeneticVariation BEFREE Association between BDNF polymorphism (Val66Met) and executive function in patients with amnestic mild cognitive impairment or mild Alzheimer disease. 22699449

2012

dbSNP: rs759834365
rs759834365
0.060 GeneticVariation BEFREE Although Val66Met polymorphisms were not associated with the cross-sectional diagnoses of MCI or AD, the presence of Met-BDNF allele was associated with a higher risk of disease-progression in patients with MCI (OR=3.0 CI(95%) [1.2-7.8], P=0.02). 20491609

2010

dbSNP: rs759834365
rs759834365
0.060 GeneticVariation BEFREE The BDNF Val66Met polymorphism was not associated with serum BDNF or cognitive function in aMCI patients. 18505307

2008