Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
0.060 GeneticVariation BEFREE H63D mutation did not significantly increase overall cance</span>r risk in any genetic model. 26893171

2016
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
0.060 GeneticVariation BEFREE Statistically significant associations were identified between the HFE H63D polymorphism and solid cancer risk (CG vs CC, OR = 1.14, 95%CI = 1.07-1.23, P < 0.001; GG vs CC, OR = 1.28, 95%CI = 1.06-1.55, P = 0.010; CG/GG vs CC, OR = 1.16, 95%CI = 1.08-1.24, P < 0.001; GG vs CC/CG, OR = 1.24, 95%CI = 1.02-1.49, P = 0.027). 26535689

2015
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
0.060 GeneticVariation BEFREE Present study suggested that H63D and C282Y polymorphisms associated with an increased risk of overall cancer. 26107216

2015
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
0.060 GeneticVariation BEFREE Two frequent mutations in the HFE gene, H63D and C282Y, are associated with hemochromatosis type I, an inherited iron overload disease and, possibly, with cancer. 20669231

2011
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
0.060 GeneticVariation BEFREE Possible association between the C282Y and H63D mutations in the HFE gene and estrogen-dependent cancer risk was assessed. 16216474

2006
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
0.060 GeneticVariation BEFREE We sought to compare frequencies of HFE C282Y and H63D alleles and associated odds ratios (OR) in 100 consecutive unrelated white adults with malignancy to those in 318 controls. 15018631

2004