|
rs1899663
|
|
|
0.070 |
GeneticVariation |
BEFREE |
We conducted an up-to-date meta-analysis to pool eligible studies and to further explore the possible relationships between HOTAIR polymorphisms (rs920778, rs7958904, rs12826786, 4,759,314, rs874945, and rs1899663) and cancer risk.
|
29463216 |
2018 |
|
rs1899663
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The results showed that cancer risk was elevated in recessive mutation of rs12826786 (TT vs CC+CT: OR =1.55, 95% CI =1.19, 2.03; TT+CT vs CC: OR =1.23, 95% CI =1.04, 1.46; TT vs CC: OR =1.67, 95% CI =1.24, 2.24; T vs C: OR =1.24, 95% CI =1.09, 1.40) and rs920778 (TT vs CC+CT: OR =1.73, 95% CI =1.30, 2.30; TT+CT vs CC: OR =1.40, 95% CI =1.16, 1.70; TT vs CC: OR =1.83, 95% CI =1.25, 2.68; T vs C: OR =1.37, 95% CI =1.18, 1.59), while the results for polymorphisms of rs7958904, rs4759314, rs874945, and rs1899663 were insignificant.
|
29497311 |
2018 |
|
rs1899663
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Comparison between prostate cancer and BPH groups showed that rs1899663 is associated with cancer risk in co-dominant, dominant and recessive inheritance models.
|
28259691 |
2017 |
|
rs1899663
|
|
|
0.070 |
GeneticVariation |
BEFREE |
rs920778, rs7958904 and rs874945 but not rs4759314 and rs1899663 loci were significantly related to cancer risk, among of which rs920778 and rs874945 increased and rs7958904 decreased cancer risk, respectively.
|
27965458 |
2017 |
|
rs1899663
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In addition, lack of association was detected between rs1899663 polymorphism and cancer susceptibility.
|
28938673 |
2017 |
|
rs1899663
|
|
|
0.070 |
GeneticVariation |
BEFREE |
However, no significant association was identified between the rs874945, rs4759314 and rs1899663 polymorphisms and cancer susceptibility.
|
27791260 |
2017 |
|
rs1899663
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Overall, no significant associations between the HOTAIR polymorphisms (rs920778, rs4759314 and rs1899663) and cancer risk were observed.
|
27010768 |
2016 |