rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We have previously found association between the ABCB1 C-rs3789243-T polymorphism and CRC risk and interactions between the ABCB1 C-rs3789243-T and C3435T polymorphisms and meat intake in relation to CRC risk (Andersen, BMC Cancer, 2009, 9, 407).
|
23977225 |
2013 |
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In summary, this meta-analysis suggests that the MDR1 C3435T polymorphism is associated with cancer susceptibility, increasing the risk of breast and renal cancer.
|
22358302 |
2012 |
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The results suggested that the MDR1 C3435T polymorphism may contribute to cancer risk.
|
22311042 |
2012 |
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The C3435T polymorphism of the MDR1 gene may influence the transport and excretion of carcinogens, increasing the risk of cancer.
|
22641402 |
2012 |
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We therefore investigated the influence of polymorphisms G1199A, C1236T, G2677T/A and C3435T on cancer susceptibility, in vitro cytotoxicity and overall survival in 100 de novo AML patients with normal karyotype.
|
20938465 |
2012 |
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Polymorphism ABCB1 (3435C>T) may be a prediction marker of cancer chemotherapy effectiveness.
|
19415305 |
2009 |
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Recently, association between the MDR1 C3435T polymorphism and the cancer susceptibility was shown.
|
17300681 |
2007 |
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the incidence of C3435T polymorphisms at exon 26 in the MDR-1 gene in 92 women with breast cancer and potential association of altered genotypes with smoking and high body mass index in cancer development among patients.
|
17549370 |
2007 |
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The importance of MDR1 SNPs 2677G > T/A in exon 21 and 3435C > T in exon 26 for cancer susceptibility, however, has not yet been clearly defined.
|
17146660 |
2007 |
rs1045642
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggest that ABCB1 3435C>T polymorphism is associated with antiemetic treatment efficacy in patients with cancer treated with 5-HT(3) antagonists, particularly in granisetron-treated patients, during the short-term phase of chemotherapy.
|
16338277 |
2005 |
rs3789243
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We have previously found association between the ABCB1 C-rs3789243-T polymorphism and CRC risk and interactions between the ABCB1 C-rs3789243-T and C3435T polymorphisms and meat intake in relation to CRC risk (Andersen, BMC Cancer, 2009, 9, 407).
|
23977225 |
2013 |
rs3789243
|
|
|
0.020 |
GeneticVariation |
BEFREE |
No association was found between the MDR1 polymorphism (G-rs3789243-A) and colorectal adenomas or cancer.
|
19250544 |
2009 |
rs3842
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, stratification analysis demonstrated a remarkable association of ABCB1 rs3842 with the risk of cancer manifested in women (OR, 2.57; 95% CI, 1.36-4.85), in the histologic type of adenocarcinoma (OR, 1.42; 95% CI, 1.03-1.99), and in individuals aged <60 years (OR, 1.50; 95% CI, 1.05-2.14).
|
19107762 |
2009 |
rs2229109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We and others have reported a number of functionally significant MDR1 variants, including G1199A and G1199T, that modulate cancer drug resistance and intracellular levels of antivirals.
|
18723777 |
2008 |
rs2032582
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The importance of MDR1 SNPs 2677G > T/A in exon 21 and 3435C > T in exon 26 for cancer susceptibility, however, has not yet been clearly defined.
|
17146660 |
2007 |