| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.050 | GeneticVariation | BEFREE | Simultaneously, rs2279115 was correlated with a significantly higher risk of cancer prognosis in Asia but not in Caucasian. | 28445963 | 2017 |
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|
0.050 | GeneticVariation | BEFREE | A functional single-nucleotide polymorphism (c.-938C>A, rs2279115) in the inhibitory P2 BCL2 gene promoter has been associated with clinical outcomes in various types of cancer. | 28396899 | 2017 |
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|
0.050 | GeneticVariation | BEFREE | Our results indicate that the BCL-2 rs2279115 genetic variant was associated with SCLC risk in Chinese populations and support the hypothesis that SNPs in regulatory regions of oncogenes might contribute to cancer susceptibility. | 26311051 | 2016 |
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|
0.050 | GeneticVariation | BEFREE | Multiple functional BCL-2 genetic polymorphisms, such as rs2279115, rs1801018 and rs1564483, have been identified previously and might be involved in cancer development through deregulating BCL-2 expression. | 26132559 | 2015 |
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|
0.050 | GeneticVariation | BEFREE | This meta-analysis was performed to evaluate the relationships of Bcl-2 -938 C>A polymorphism (rs2279115) with susceptibility and prognosis of cancer. | 25430556 | 2014 |
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|
0.010 | GeneticVariation | BEFREE | Our results showed statistically significant association between rs2279115 and cancer susceptibility and prognosis in all four genetic models but not in rs1801018. | 28445963 | 2017 |
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|
0.010 | GeneticVariation | BEFREE | Multiple functional BCL-2 genetic polymorphisms, such as rs2279115, rs1801018 and rs1564483, have been identified previously and might be involved in cancer development through deregulating BCL-2 expression. | 26132559 | 2015 |