|
rs187115
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Collectively, the CD44 rs187115</span> variant may be associated with the risk of cervical, lung, and liver cancer in the central Chinese population, and may be used as a potential biomarker for cancer predisposition in the Asian population, especially in the Chinese population.
|
30860617 |
2019 |
|
rs187115
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Moreover, CD44 gene rs187115 polymorphism appears to be genetic determinant of cancer susceptibility.
|
31682231 |
2019 |
|
rs187115
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Nevertheless, the pooled analyses suggested that no significant association was uncovered between CD44 (rs10836347, rs11821102, rs13347, rs1425802, rs353639, rs713330 and rs187115) polymorphisms with overall cancer risk.
|
27738347 |
2016 |
|
rs187115
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Based on our analysis, we suggest significant role of CD44 variants (rs13347, rs187115 and rs11821102) in modulating individual's cancer susceptibility in Asians.
|
27521214 |
2016 |
|
rs13347
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Subsequently, we conducted subgroup analysis for rs13347 polymorphism based on source of control, and we identified a significantly increased cancer risk for the population-based (P-B) group restricted to a recessive model (TT vs. TC+CC: OR = 2.030, 95%CI: 1.163-3.545, PAdjust < 0.001).
|
27738347 |
2016 |
|
rs13347
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In conclusion, the results indicate that CD44 polymorphism rs13347 acts as a risk factor for cancer, especially in Chinese, while the minor allele of polymorphism rs11821102 may be associated with a decreased susceptibility to cancer.
|
28000766 |
2016 |
|
rs13347
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Based on our analysis, we suggest significant role of CD44 variants (rs13347, rs187115 and rs11821102) in modulating individual's cancer susceptibility in Asians.
|
27521214 |
2016 |
|
rs11821102
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the results indicate that CD44 polymorphism rs13347 acts as a risk factor for cancer, especially in Chinese, while the minor allele of polymorphism rs11821102 may be associated with a decreased susceptibility to cancer.
|
28000766 |
2016 |
|
rs11821102
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Based on our analysis, we suggest significant role of CD44 variants (rs13347, rs187115 and rs11821102) in modulating individual's cancer susceptibility in Asians.
|
27521214 |
2016 |
|
rs713330
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Additionally, the minor allele of polymorphism rs11821102 was associated with a decreased susceptibility to cancer in allele contrast, dominant, and heterozygous models, while no significant association was identified for polymorphisms rs10836347, rs713330, or rs1425802.
|
28000766 |
2016 |
|
rs713330
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Nevertheless, the pooled analyses suggested that no significant association was uncovered between CD44 (rs10836347, rs11821102, rs13347, rs1425802, rs353639, rs713330 and rs187115) polymorphisms with overall cancer risk.
|
27738347 |
2016 |
|
rs751144688
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three of them CD44, S100A7, and S100P were significantly altered in patients with LP as well as OSCC and can be regarded as a panel of biomarker candidates for early detection of the malignancy.
|
31706945 |
2020 |
|
rs8193
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs8193 is statistically associated with the risk of malignancy, lymph node spread and stage of gastric cancer in Iranian population.
|
31376327 |
2020 |
|
rs10836347
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, the minor allele of polymorphism rs11821102 was associated with a decreased susceptibility to cancer in allele contrast, dominant, and heterozygous models, while no significant association was identified for polymorphisms rs10836347, rs713330, or rs1425802.
|
28000766 |
2016 |