|
rs13181
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We have described statistically significant interactions between the ERCC2 polymorphisms (Asp312Asn and Lys751Gln) and smoking in lung cancer risk.
|
12692111 |
2003 |
|
rs1799793
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We have described statistically significant interactions between the ERCC2 polymorphisms (Asp312Asn and Lys751Gln) and smoking in lung cancer risk.
|
12692111 |
2003 |
|
rs25487
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this case-control study of 1091 Caucasian lung cancer patients and 1240 controls, we explored the gene-environment interactions between the XRCC1 Arg399Gln polymorphism, alone or in combination with the two ERCC2 polymorphisms, and cumulative smoking exposure in the development of lung cancer.
|
12692111 |
2003 |
|
rs759412116
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In this case-control study of 1091 Caucasian lung cancer patients and 1240 controls, we explored the gene-environment interactions between the XRCC1 Arg399Gln polymorphism, alone or in combination with the two ERCC2 polymorphisms, and cumulative smoking exposure in the development of lung cancer.
|
12692111 |
2003 |
|
rs1048943
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The odds ratio (OR) of lung cancer for the variant CYP1A1 Ile(462)Val polymorphism (Ile/Val, Val/Val) was 2.99 [95% confidence interval (95%CI) 1.51-5.91]; this effect was stronger on lung adenocarcinoma (OR 4.85, 95%CI 2.03-11.6).
|
12771031 |
2003 |
|
rs17655
|
|
|
0.070 |
GeneticVariation |
BEFREE |
We investigated the relationship between the His1104Asp polymorphism in the XPG gene and the risk of lung cancer.
|
12869423 |
2003 |
|
rs63750447
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To our knowledge, this is for the first time that the T1151A mutation is found in lung cancer.
|
12874865 |
2003 |
|
rs3219489
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We identified three common coding region (V22M, Q324H and S501F) and intronic (157+30A>G, 462+35G>A and 1435-40G>C) variants, but none were over-represented in the patient samples, indicating that MYH variants are unlikely to predispose significantly to the risk of lung cancer.
|
14579148 |
2004 |
|
rs1060503291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified three common coding region (V22M, Q324H and S501F) and intronic (157+30A>G, 462+35G>A and 1435-40G>C) variants, but none were over-represented in the patient samples, indicating that MYH variants are unlikely to predispose significantly to the risk of lung cancer.
|
14579148 |
2004 |
|
rs140118273
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified three common coding region (V22M, Q324H and S501F) and intronic (157+30A>G, 462+35G>A and 1435-40G>C) variants, but none were over-represented in the patient samples, indicating that MYH variants are unlikely to predispose significantly to the risk of lung cancer.
|
14579148 |
2004 |
|
rs3219484
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified three common coding region (V22M, Q324H and S501F) and intronic (157+30A>G, 462+35G>A and 1435-40G>C) variants, but none were over-represented in the patient samples, indicating that MYH variants are unlikely to predispose significantly to the risk of lung cancer.
|
14579148 |
2004 |
|
rs776197565
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified three common coding region (V22M, Q324H and S501F) and intronic (157+30A>G, 462+35G>A and 1435-40G>C) variants, but none were over-represented in the patient samples, indicating that MYH variants are unlikely to predispose significantly to the risk of lung cancer.
|
14579148 |
2004 |
|
rs9282861
|
|
|
0.050 |
GeneticVariation |
BEFREE |
A functional polymorphism in the SULT1A1 gene (G638A) is associated with risk of lung cancer in relation to tobacco smoking.
|
14688021 |
2004 |
|
rs1042028
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A functional polymorphism in the SULT1A1 gene (G638A) is associated with risk of lung cancer in relation to tobacco smoking.
|
14688021 |
2004 |
|
rs13181
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Among men, carriers of the variant allele of XPD Lys751Gln</span> had a non-significantly increased risk of lung cancer</span> in the youngest age interval (RR=6.38, 95% CI=0.74-54.90).
|
14757194 |
2004 |
|
rs1799793
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In a case-cohort study, we have investigated the occurrence of lung cancer in relation to a high-risk haplotype, previously identified for breast cancer among post-menopausal women, and in relation to the closely linked polymorphisms XPD Asp312Asn and Lys751Gln.
|
14757194 |
2004 |
|
rs1217691063
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The methylenetetrahydrofolate reductase 677C-->T polymorphism and lung cancer risk in a Chinese population.
|
14981981 |
2004 |
|
rs1130409
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggest that APE1 Asp148Glu and XRCC1 Arg399Gln polymorphisms might modify the risk of lung cancer attributable to cigarette smoking exposure.
|
15044328 |
2004 |
|
rs25487
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggest that APE1 Asp148Glu and XRCC1 Arg399Gln polymorphisms might modify the risk of lung cancer attributable to cigarette smoking exposure.
|
15044328 |
2004 |
|
rs1695
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In a population-based case-cohort study where cases and the subcohort sample were matched on duration of smoking, we investigated the occurrence of lung cancer and histological subtypes of lung cancer in relation to deletion polymorphism in both GSTM1 and GSTT1, single nucleotide polymorphisms (SNPs) in GSTP1 (Ile105Val and Ala114Val) and a 3 base pair deletion polymorphism in GSTM3.
|
15069685 |
2004 |
|
rs1138272
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In a population-based case-cohort study where cases and the subcohort sample were matched on duration of smoking, we investigated the occurrence of lung cancer and histological subtypes of lung cancer in relation to deletion polymorphism in both GSTM1 and GSTT1, single nucleotide polymorphisms (SNPs) in GSTP1 (Ile105Val and Ala114Val) and a 3 base pair deletion polymorphism in GSTM3.
|
15069685 |
2004 |
|
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggest that the hOGG1 Ser326Cys polymorphism plays an important role in the risk for lung cancer and is linked to exposure to tobacco smoke.
|
15077011 |
2004 |
|
rs1326656542
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These results suggest that the hOGG1 Ser326Cys polymorphism plays an important role in the risk for lung cancer and is linked to exposure to tobacco smoke.
|
15077011 |
2004 |
|
rs1052133
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We therefore examined the association between single nucleotide polymorphisms (SNPs) in four genes (AKR1C3-Gln5His, NQO1-Pro187Ser, MnSOD-Val16Ala and OGG1-Ser326Cys) that play a role in the generation, prevention or repair of oxidative damage and lung cancer risk in a population-based, case-control study of 119 cases and 113 controls in Xuan Wei, China.
|
15284179 |
2004 |
|
rs4880
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We therefore examined the association between single nucleotide polymorphisms (SNPs) in four genes (AKR1C3-Gln5His, NQO1-Pro187Ser, MnSOD-Val16Ala and OGG1-Ser326Cys) that play a role in the generation, prevention or repair of oxidative damage and lung cancer risk in a population-based, case-control study of 119 cases and 113 controls in Xuan Wei, China.
|
15284179 |
2004 |