Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE GSTP1 Ile105Val polymorphism might be associated with the risk of radiation pneumonitis among lung cancer patients in Chinese population: A prospective study. 29556330

2018

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE GSTP1 Ile105Val was associated with increased lung function, reduced risk for lung cancer and tobacco-related cancer, and reduced all-cause mortality in the general population. 28739440

2017

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE The analysis results showed that the following polymorphisms were correlated with susceptibility to lung cancer: rs4646903 in CYP1A1 (P < 0.001), rs1048943 in CYP1A1 (P < 0.001), rs1695 in GSTP1 (P < 0.05), rs13181 in ERCC2 (P < 0.001), and rs25487 in XRCC1 (P < 0.05); no such correlation existed in rs861539 in XRCC3 (P > 0.05). 27819744

2016

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE This meta-analysis suggests that GSTP1 Ile105Val polymorphism may increase the risk of lung cancer in the Chinese population. 26458582

2016

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE Overall, there is no evidence showing a significant correlation between GSTP1 Ile105Val gene polymorphism and lung cancer risk in overall population, however stratified analysis by ethnicity, histology, gender and smoking status, it correlate with increased lung cancer susceptibility among Asians and smokers. 24566690

2014

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE The results of the analysis of gene-gene interactions of CYP1A1 MspI T6235C, GSTM1 present/null, GSTT1 present/null and GSTP1 Ile105Val polymorphisms in lung cancer risk indicate that these genes do not interact in lung cancer development. 23013535

2012

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE CYP1A1 rs4646903 (OR = 1.72, 95% CI = 1.25-2.38), rs1048943 (OR = 1.40, 95% CI = 1.02-1.92), the GSTM1 deletion polymorphism (OR = 1.38, 95% CI = 1.01-1.89), GSTP1 rs1695 (OR =1.48, 95% CI = 1.04-2.11), ERCC2 rs13181 (OR = 1.89, 95% CI = 1.28-2.78), and Chinese hamster 1 rs25487 (OR = 1.54, 95% CI = 1.12-2.13) were associated with lung cancer risk whereas the GSTT1 deletion polymorphism and XRCC3 rs861539 were not. 22525558

2012

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE This meta-analysis suggested that there might be an association between GSTP1 Ile105Val polymorphism and lung cancer in the Chinese Han population. 22797821

2012

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE MDR analysis identified two distinct predictor models for the risk of lung cancer in smokers (tobacco chewing, EPHX1 Tyr113His, and SULT1A1 Arg213His) and non-smokers (CYP1A1*2A, GSTP1 Ile105Val and SULT1A1 Arg213His) with testing balance accuracy (TBA) of 0.6436 and 0.6677 respectively. 22206016

2011

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE No overall association between lung cancer and GSTT1 null or GSTP1 Ile105Val was found. 20729793

2010

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE The polymorphisms of GSTP1 Ile105Val and MPO G-463A showed no significant association with lung cancer. 17980933

2008

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE The risk of lung cancer is not strongly associated with the I105V and A114V polymorphisms in the GSTP1 gene or with GSTM3 intron 6 polymorphism. 16509765

2006

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE GSTP1 Ile105Val and hOGG1 Ser326Cys polymorphisms were not found to be risk factors of lung cancer in this study. 15896461

2005

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE In a population-based case-cohort study where cases and the subcohort sample were matched on duration of smoking, we investigated the occurrence of lung cancer and histological subtypes of lung cancer in relation to deletion polymorphism in both GSTM1 and GSTT1, single nucleotide polymorphisms (SNPs) in GSTP1 (Ile105Val and Ala114Val) and a 3 base pair deletion polymorphism in GSTM3. 15069685

2004

dbSNP: rs1695
rs1695
0.100 GeneticVariation BEFREE In this study we have addressed the possible role of the Ile105Val GSTP1 polymorphism in lung cancer susceptibility. 10334644

1999