Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.040 GeneticVariation BEFREE RESULTS The results obtained from this study demonstrated that XRCC1-77TC + CC, XRCC1 399Gln/Gln, COMT 186CT + TT, COMT 158Val/Met genotypes, type of occupation, cooking-oil fumes, and soot exposures were all independent risk factors involved with the occurrence of lung cancer among non-smoking women. 30109864

2018
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.040 GeneticVariation BEFREE Our findings indicate that CYP2E1 rs2031920 and COMT rs4680 are not major contributors to lung cancer risk in our Japanese population. 27644662

2016
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.040 GeneticVariation BEFREE Five publications, including six individual studies with a total of 4,043 subjects (1,796 cases and 2,247 controls) regarding the association of COMT Val158Met polymorphism with lung cancer susceptibility were included in this meta-analysis. 25280560

2014
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.040 GeneticVariation BEFREE The COMT rs4680 A allele was positively associated with lung cancer in never smokers (for G/A or A/A vs. G/G, OR = 1.46, 95% CI: 1.12, 1.90) but not in ever smokers. 22331461

2012