The TGF-β1 T + 869C (rs1982073) and C-509T (rs1800469</span>) polymorphisms are not implicated in lung cancer susceptibility in the overall population.
To test this hypothesis, we investigated the association of the TGF-beta1 -509C > T and 869T > C (L10P) polymorphisms and their haplotypes with the risk of lung cancer in a Korean population.
The presence of different rs7459185/rs11466353 genotypes in LC patients associated with RIET risk and may be useful biomarkers along with other risk factors for guiding therapy intensity in an individualized therapy.