rs77375493
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The V617F JAK2 mutation was absent within the patients with secondary erythrocytosis or thrombocytosis.
|
19939582 |
2011 |
rs77375493
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The Janus kinase 2 (JAK2) V617F mutation was present in 34 (85.3%) PV, 2 (50%) IE, 1 (50%) apparent and no secondary erythrocytosis cases.
|
17454193 |
2007 |
rs77375493
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We could confirm a very high sensitivity, specificity and utility of the Jak2(V617F) mutation for differential diagnosis between PV and SE.
|
17852451 |
2007 |
rs77375493
|
|
|
0.060 |
GeneticVariation |
BEFREE |
However, until the recent description of the constitutively activating V617F point mutation of the Janus 2 tyrosine kinase (JAK2)--a high-frequency molecular marker that is extremely specific for clonal chronic myeloproliferative disorders--distinction of PV from secondary erythrocytosis or other conditions has often been difficult.
|
16827884 |
2006 |
rs77375493
|
|
|
0.060 |
GeneticVariation |
BEFREE |
However, compared with the PRV-1 assay, mutation screening for JAK2(V617F) displayed greater accuracy in distinguishing PV from SP.
|
16197445 |
2005 |
rs77375493
|
|
|
0.060 |
GeneticVariation |
BEFREE |
V617F was not identified in patients with systemic mastocytosis (n = 28), chronic or acute myeloid leukemia (n = 35), secondary erythrocytosis (n = 4), or healthy controls (n = 160).
|
15920007 |
2005 |
rs1253570532
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, the level of RUNX1/AML1 and NF-E2 transcripts that are specifically upregulated in acquired polycythemia vera were also upregulated in VHL(P138L) granulocytes.
|
23538339 |
2013 |
rs772889171
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, the level of RUNX1/AML1 and NF-E2 transcripts that are specifically upregulated in acquired polycythemia vera were also upregulated in VHL(P138L) granulocytes.
|
23538339 |
2013 |
rs775387828
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, the level of RUNX1/AML1 and NF-E2 transcripts that are specifically upregulated in acquired polycythemia vera were also upregulated in VHL(P138L) granulocytes.
|
23538339 |
2013 |
rs780178275
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, the level of RUNX1/AML1 and NF-E2 transcripts that are specifically upregulated in acquired polycythemia vera were also upregulated in VHL(P138L) granulocytes.
|
23538339 |
2013 |
rs1035193069
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hb Kempsey (beta 99 Asp----Asn) is a high-oxygen affinity hemoglobin, never before reported in Italy, associated with secondary erythrocytosis.
|
1427427 |
1992 |
rs759442241
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hb Kempsey (beta 99 Asp----Asn) is a high-oxygen affinity hemoglobin, never before reported in Italy, associated with secondary erythrocytosis.
|
1427427 |
1992 |
rs779735456
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hb Kempsey (beta 99 Asp----Asn) is a high-oxygen affinity hemoglobin, never before reported in Italy, associated with secondary erythrocytosis.
|
1427427 |
1992 |