Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11540652
rs11540652
0.020 GeneticVariation BEFREE We previously showed that the HSP90 inhibitor ganetespib potently suppresses T-lymphoma initiation and progression and extends overall survival (OS) in hotspot knockin mice expressing the p53 gain-of-function mutants R175H and R248Q (mutp53) by 30-59%. 28300840

2017

dbSNP: rs11540652
rs11540652
0.020 GeneticVariation BEFREE This was associated with a twofold higher T-lymphoma proliferation in R248Q/- mice compared with G245S/- and null mice. 23538418

2013