Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10074991
rs10074991
G 0.700 GeneticVariation GWASCAT Genome-wide association study of gastric adenocarcinoma in Asia: a comparison of associations between cardia and non-cardia tumours. 26129866

2016

dbSNP: rs2031920
rs2031920
0.010 GeneticVariation BEFREE The <i>CYP1A1</i> rs4646903 and <i>CYP2E1</i> rs2031920 polymorphisms were risk factors of GCC or EC, and the <i>GSTM1</i> null genotype may serve a protective role against EC. 31423187

2019

dbSNP: rs4646903
rs4646903
0.010 GeneticVariation BEFREE The <i>CYP1A1</i> rs4646903 and <i>CYP2E1</i> rs2031920 polymorphisms were risk factors of GCC or EC, and the <i>GSTM1</i> null genotype may serve a protective role against EC. 31423187

2019

dbSNP: rs115797771
rs115797771
0.010 GeneticVariation BEFREE Two novel variants, rs1924966 and rs115797771, were associated with ESCC risk (P = 1.37 × 10(-10) and P = 2.32 × 10(-10), respectively) and were also associated with risk of gastric cardia cancer (P = 0.0003 and P = 0.0018, respectively) but not gastric cancer and colorectal cancer. 26315552

2015

dbSNP: rs1924966
rs1924966
0.010 GeneticVariation BEFREE Two novel variants, rs1924966 and rs115797771, were associated with ESCC risk (P = 1.37 × 10(-10) and P = 2.32 × 10(-10), respectively) and were also associated with risk of gastric cardia cancer (P = 0.0003 and P = 0.0018, respectively) but not gastric cancer and colorectal cancer. 26315552

2015

dbSNP: rs1217691063
rs1217691063
0.010 GeneticVariation BEFREE Stratification by tumor site showed an association between the C677T polymorphism and gastric cardia cancer and non-cardia GC in the worldwide population and in eastern populations. 25170232

2014

dbSNP: rs2274223
rs2274223
0.010 GeneticVariation BEFREE In a subgroup analysis, the PLCE1 rs2274223 polymorphism was found to be a very sensitive marker for gastric cardia cancer as shown by the homozygous genetic model (OR = 2.23), heterozygous genetic model(OR = 1.59) and allelic genetic model (OR = 1.47). 23826241

2013

dbSNP: rs1042522
rs1042522
0.010 GeneticVariation BEFREE Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. 17638920

2007

dbSNP: rs1131691014
rs1131691014
0.010 GeneticVariation BEFREE Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. 17638920

2007

dbSNP: rs1353702185
rs1353702185
0.010 GeneticVariation BEFREE Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. 17638920

2007

dbSNP: rs878854066
rs878854066
0.010 GeneticVariation BEFREE Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. 17638920

2007

dbSNP: rs1799782
rs1799782
0.010 GeneticVariation BEFREE We observed no association between the variant genotype in XRCC1 Arg194Trp (codon 194 arganine to tryptophan substitution) and esophageal or gastric cardia cancer. 15533591

2004

dbSNP: rs25487
rs25487
0.010 GeneticVariation BEFREE However, carrying at least one copy of the variant allele in XRCC1 Arg399Gln (codon 399 arganine to glutamine substitution) was associated with reduced risk of gastric cardia cancer (RR: 0.60, 95% CI: 0.37-0.97) and the combined category esophageal/gastric cancer (RR: 0.67, 95% CI: 0.48-0.95). 15533591

2004