| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.700 | GeneticVariation | UNIPROT | ACMG policy statement: updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing. | 25356965 | 2015 |
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|
0.700 | GeneticVariation | UNIPROT | Four new mutations in the DNA mismatch repair gene MLH1 in colorectal cancers with microsatellite instability. Mutations in brief no. 157. Online. | 10627141 | 1998 |
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|
0.700 | GeneticVariation | UNIPROT | Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16. | 8571956 | 1996 |
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|
0.700 | GeneticVariation | UNIPROT | ACMG technical standards and guidelines for genetic testing for inherited colorectal cancer (Lynch syndrome, familial adenomatous polyposis, and MYH-associated polyposis). | 24310308 | 2014 |
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|
0.700 | GeneticVariation | UNIPROT | Excess of hMLH1 germline mutations in Swiss families with hereditary non-polyposis colorectal cancer. | 9833759 | 1998 |
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|
0.700 | GeneticVariation | UNIPROT | Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-society Task Force on colorectal cancer. | 25070057 | 2014 |
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|
0.700 | GeneticVariation | UNIPROT | Practice parameters for the identification and testing of patients at risk for dominantly inherited colorectal cancer--supporting documentation. | 11598466 | 2001 |
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|
0.700 | GeneticVariation | UNIPROT | Hereditary colorectal cancer syndromes: American Society of Clinical Oncology Clinical Practice Guideline endorsement of the familial risk-colorectal cancer: European Society for Medical Oncology Clinical Practice Guidelines. | 25452455 | 2015 |
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|
0.700 | GeneticVariation | UNIPROT | Germline mutations in MLH1, MSH2 and MSH6 in Korean hereditary non-polyposis colorectal cancer families. | 15365995 | 2004 |
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|
0.700 | GeneticVariation | UNIPROT | Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts. | 23408351 | 2013 |