Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE BRAF V600E Status and Stimulated Thyroglobulin at Ablation Time Increase Prognostic Value of American Thyroid Association Classification Systems for Persistent Disease in Differentiated Thyroid Carcinoma. 31093278

2019

dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE The genetic duet of BRAF V600E/RAS and TERT promoter mutations is a most robust prognostic genetic pattern for poor prognosis of differentiated thyroid cancer. 30717896

2019

dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE Our results show a high rate and a strong prognostic role of the classical BRAF (V600E) mutation and also suggest a common occurrence of non-hot spot mutations in adult DTC from this highly inbred population. 27387551

2016

dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE These data suggest that BRAF(V600E)-mutated DTCs are significantly more (18)F-FDG-avid than BRAF-WT tumors. 25814520

2015

dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE Neither the presence of V600E BRAF mutations nor that of a well-differentiated thyroid carcinoma changed the outcome or disease-free survival. 24777145

2014

dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE This study investigated the role of molecular studies in preoperative diagnosis of DTC and</span> the association of p.V600E mutation with prognostic factors. 24468978

2014

dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE We found TERT promoter mutations in 0.0% (0/179) of benign thyroid nodules and 7.0% (9/129) of thyroid nodules of differentiated thyroid cancer, representing a 100% diagnostic specificity and 7.0% sensitivity, with the latter rising to 38.0% (49/129) when combined with BRAF V600E testing. 25121551

2014

dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE The aims of this study were to evaluate the utility of US-guided FNAB in the diagnostic assessment of nodules with or without clinical/US features suggestive for malignancy and to investigate the additional contribution of BRAF V600E mutation analysis in the detection of differentiated thyroid cancer. 22535974

2012

dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE Role of B-Raf(V600E) in differentiated thyroid cancer and preclinical validation of compounds against B-Raf(V600E). 19356676

2009

dbSNP: rs113488022
rs113488022
0.100 GeneticVariation BEFREE DTC was present in half of the cases.BRAF V600E mutation was identified in nine of 36 (25%) ATCs; seven cases had identical mutations in both the ATC and DTC components. 17989125

2008