|
rs11787216
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Identification of common genetic risk variants for autism spectrum disorder.
|
30804558 |
2019 |
|
rs13294439
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Identification of common genetic risk variants for autism spectrum disorder.
|
30804558 |
2019 |
|
rs2388334
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Identification of common genetic risk variants for autism spectrum disorder.
|
30804558 |
2019 |
|
rs4307059
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Individuals who carry the ASD-associated rs4307059 T allele showed increased expression of MSNP1AS.
|
22491950 |
2012 |
|
rs4307059
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The association of rs4307059 and rs35678 markers with autism spectrum disorders is replicated in Italian families.
|
22739633 |
2012 |
|
rs4307059
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results suggest that common variation at 5p14.1 is associated with social communication spectrum phenotypes in the general population and support the role of rs4307059 as a quantitative trait locus for autism spectrum disorder.
|
20634369 |
2010 |
|
rs12826786
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on the results of the current investigation, the rs12826786 can be regarded as a risk locus for ASD in Iranian population.
|
31654274 |
2020 |
|
rs13000344
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Similarly, in OTX1, rs2018650 and rs13000344 were associated with autism in ASD-CARC cohorts (P(FDR)=8.65 × 10(-7) and 6.07 × 10(5), respectively), AGRE cohort (P(FDR)=0.0034 and 0.015, respectively) and the combined families (P(FDR)=2.34 × 10(-9) and 0.00017, respectively); associations were marginal or insignificant in the New York and SIRFA cohorts.
|
21750575 |
2011 |
|
rs194085
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Family-based association testing and haplotype analysis revealed a statistically significant association between rs194085 and multiple sociality traits with Korean ASDs in the dominant model (p<0.001, corrected p=0.035).
|
29209394 |
2017 |
|
rs34808376
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we have investigated the association of five markers [rs3735653 (C/T) in exon 1; rs34808376 (GC/-) and rs6150410 (CGCATCCCC/-) in promoter region; rs1861972 (A/G) and rs1861973 (C/T) in the intron] of the gene with autism and ASD in Indian population using family-based approach.
|
20050924 |
2010 |
|
rs35753505
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine the genetic association between qualitative and quantitative traits of autism spectrum disorder (ASD) and neuregulin 1 (NRG1)-a schizophrenia candidate gene-we examined six single nucleotide polymorphisms (SNPs) in NRG1 using a family-based association test (FBAT) in Korean families with ASD. rs35753505 and rs6994992 SNPs in NRG1 revealed a statistically significant family-based association with three quantitative traits for sociality.
|
25858800 |
2015 |
|
rs6150410
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we have investigated the association of five markers [rs3735653 (C/T) in exon 1; rs34808376 (GC/-) and rs6150410 (CGCATCCCC/-) in promoter region; rs1861972 (A/G) and rs1861973 (C/T) in the intron] of the gene with autism and ASD in Indian population using family-based approach.
|
20050924 |
2010 |
|
rs379863
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It was expected that risk-allele-carriers of the oxytocin-receptor-gene-polymorphism (rs53576) and of CD38 (rs379863) responded similar to upright and inverted faces as persons with ASD.
|
27015428 |
2016 |
|
rs73598374
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The G22A polymorphism of the ADA gene and susceptibility to autism spectrum disorders.
|
17340203 |
2008 |
|
rs6551665
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We tested the association of an ADGRL3 variant (rs6551665</span>) with both early-onset ADHD and ASD susceptibility.
|
30652248 |
2019 |
|
rs2236624
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Nominal association with the disorder was observed for rs2236624-CC, and phenotypic variability in ASD symptoms was influenced by rs3761422, rs5751876 and rs35320474.
|
19565319 |
2010 |
|
rs765619798
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We detected a statistically significant association between the variant Ala55Thr in CX3CR1 with SCZ and ASD phenotypes (odds ratio=8.3, P=0.020).
|
28763059 |
2017 |
|
rs370956755
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We detected a statistically significant association between the variant Ala55Thr in CX3CR1 with SCZ and ASD phenotypes (odds ratio=8.3, P=0.020).
|
28763059 |
2017 |
|
rs1800497
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 110 adult patients with ASD (n=61) or ADHD (n=49) with or without a lifetime history of SUD participated in a study in which we genotyped polymorphisms in five known candidate genes for (one of) the disorders, i.e. the 5HTTLPR in SLC6A4/5-HTT, rs1800497 (TaqIA C>T) in DRD2, rs7794745 in CNTNAP2, rs1843809 in TPH2, and rs6565113 in CDH13.
|
20446882 |
2010 |
|
rs766483232
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we examined the synaptic effects of rat Mint2 N723S mutation (equivalent to autism-linked human MINT2 N722S mutation) which targets a conserved asparagine residue in the second PDZ domain of Mint2 that binds to neurexin-1α (Nrxn1α), a presynaptic cell-adhesion protein implicated in ASDs.
|
30988517 |
2019 |
|
rs766483232
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we examined the synaptic effects of rat Mint2 N723S mutation (equivalent to autism-linked human MINT2 N722S mutation) which targets a conserved asparagine residue in the second PDZ domain of Mint2 that binds to neurexin-1α (Nrxn1α), a presynaptic cell-adhesion protein implicated in ASDs.
|
30988517 |
2019 |
|
rs1804197
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We serendipitously identified a single nucleotide polymorphism (SNP), 8636C>A (rs1804197) in the 3'-untranslated region of the adenomatous polyposis coli (APC) gene to be associated with autism spectrum disorder (ASD).
|
17221838 |
2007 |
|
rs465899
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In order to gain further evidence for the association between the APC locus and ASD, we genotyped four additional adjacent common SNPs (rs2229992, rs42427, rs459552, and rs465899) in the coding regions within the APC gene in a set of Swedish ASDs and controls.
|
17221838 |
2007 |
|
rs4446909
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Two polymorphisms located in the promoter (rs4446909 and rs5989681) were more frequent in ASD compared to controls (P=0.0006) and were associated with a dramatic decrease in ASMT transcripts in blood cell lines (P=2 x 10(-10)).
|
17505466 |
2008 |
|
rs4446909
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A previous study reported an association between ASD and single nucleotide polymorphisms (SNPs) rs4446909 and rs5989681 located in the promoter of ASMT.
|
23349736 |
2013 |