A total of 100 patients (mean age 57 ± 10 years [range 31-76 years]; 21% women) with diagnosed STEMI and a control group consisting of 95 healthy volunteers (mean age 38 ± 11 years [range 17-60 years]; 20% women) were investigated for the AGTR1 1166A/C polymorphism and two variants of AGT (Met235Thr and Thr174Met).
Polymorphisms of AGT Met235Thr and AGT Thr174Met genes are able to mark increased or reduced odds ratio of circumflex artery as culprit artery in STEMI.