rs202047589
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The p.Pro190Leu mutation was reported with impaired renal function at follow-up; however, the p.Gly287Val was presented with normal renal function.
|
27561601 |
2017 |
rs281874657
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The index case had the p.Q379X variant in COL4A5 and currently had renal impairment, (eGFR = 45 ml/min/1.73 m<sup>2</sup>), bilateral hearing loss, and central and peripheral retinopathies.
|
27485810 |
2017 |
rs738409
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The patatin-like phospholipase 3 (PNPLA3) polymorphism rs738409 (c.444C>G) is associated with the risk of NAFLD and/or renal dysfunction; however, the influence of the weight status on the associations remains unknown.
|
26200108 |
2015 |
rs538166970
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In contrast, another mutant, R1180P, was compatible with life after transient neonatal renal insufficiency.
|
24163131 |
2014 |
rs1382048442
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The T allele at MTHFR C677T was the risk factor for prolonged high MTX concentration (p = 0.009, OR 5.54, 95 % CI 1.54-19.85), but not for renal dysfunction.
|
24241962 |
2013 |
rs368087026
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The T allele at MTHFR C677T was the risk factor for prolonged high MTX concentration (p = 0.009, OR 5.54, 95 % CI 1.54-19.85), but not for renal dysfunction.
|
24241962 |
2013 |
rs7456421
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No statistical significance of allele transfer was found, which means that there were no associations between rs7456421 and rs 2030712 SNPs of HIPK2 gene and the incidence of renal dysfunction.
|
23540226 |
2013 |
rs7582694
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the case-only meta-analysis of the two cohorts, the STAT4 SNP rs7582694 was associated with severe renal insufficiency with p = 1.6 × 10(-3) and OR 2.22.
|
24386384 |
2013 |
rs1128503
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the CsA patient group (n = 30), age (p = 0.008), hypertension (p = 0.017), renal dysfunction (p < 0.001), ABCB1 C1236T (p < 0.001), and G2677T/A (p = 0.014) were associated with neurotoxicities.
|
20030680 |
2011 |
rs7222094
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients having the CC genotype of rs7222094 in SPH experienced more renal and hematological dysfunction (p = 0.003 and p = 0.011), while patients of the VASST cohort with the rs7222094 CC genotype showed the same trend toward more renal dysfunction.
|
21257964 |
2011 |
rs74315289
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Renal dysfunction and barttin expression in Bartter syndrome Type IV associated with a G47R mutation in BSND in a family.
|
21269598 |
2011 |
rs1617640
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our analysis suggests that the risk allele (T) of rs1617640 plays a role in the development of renal dysfunction after cardiac surgery with CPB.
|
21092038 |
2010 |
rs188942711
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The early demonstration of R229Q in individuals with TBMN may indicate those at increased risk of proteinuria and renal impairment.
|
18726620 |
2008 |
rs61747728
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The early demonstration of R229Q in individuals with TBMN may indicate those at increased risk of proteinuria and renal impairment.
|
18726620 |
2008 |
rs12026
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined the relationship between variation at the C311S and A148G polymorphisms (together with PON2 intronic variant rs12704795) and indices of renal dysfunction (progression to micro- and macroalbuminuria, plasma creatinine increases) in 3,374 newly diagnosed type 2 diabetic subjects from the UK Prospective Diabetes Study followed prospectively (median 14.0 years), using proportional hazards models, adjusted for sex, ethnicity and other known or putative risk factors.
|
17096118 |
2006 |
rs12704795
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined the relationship between variation at the C311S and A148G polymorphisms (together with PON2 intronic variant rs12704795) and indices of renal dysfunction (progression to micro- and macroalbuminuria, plasma creatinine increases) in 3,374 newly diagnosed type 2 diabetic subjects from the UK Prospective Diabetes Study followed prospectively (median 14.0 years), using proportional hazards models, adjusted for sex, ethnicity and other known or putative risk factors.
|
17096118 |
2006 |
rs34557412
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report the case of a man with CVID in association with a heterozygous TACI gene mutation (C104R) who had a highly unusual, invasive, polyclonal CD8+ T-cell lymphoproliferation resulting in massive hepatosplenomegaly and causing renal impairment because of infiltration.
|
16630947 |
2006 |
rs696217
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Leu72Met polymorphism was also associated with serum total cholesterol levels in diabetic nephropathy patients with renal</span> dysfunction; the 72Met carriers had lower total cholesterol levels than the 72Met non-carriers (P < 0.05).
|
16793966 |
2006 |
rs7493
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined the relationship between variation at the C311S and A148G polymorphisms (together with PON2 intronic variant rs12704795) and indices of renal dysfunction (progression to micro- and macroalbuminuria, plasma creatinine increases) in 3,374 newly diagnosed type 2 diabetic subjects from the UK Prospective Diabetes Study followed prospectively (median 14.0 years), using proportional hazards models, adjusted for sex, ethnicity and other known or putative risk factors.
|
17096118 |
2006 |
rs1267969615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
rs867394500
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
rs777919630
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated plasma folate and vitamin B12, methylenetetrahydrofolate reductase (MTHFR) C677T and cystathionine beta-synthase (CBS) 844ins68 polymorphisms, and homocysteine levels before and after methionine (100 mg/kg) loading in 58 patients with angiographically documented renal artery stenosis and mildly impaired renal function.
|
11918280 |
2001 |
rs1800470
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine whether genetic factors are involved in the development of renal dysfunction due to cyclosporine nephrotoxicity, we analyzed 2 polymorphisms in the signal sequence of the transforming growth factor (TGF)-beta 1 gene; codon 10 (Leu(10) --> Pro) and codon 25 (Arg(25) --> Pro).
|
11008076 |
2000 |