Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1217691063
rs1217691063
0.040 GeneticVariation BEFREE The T allele at MTHFR C677T was the risk factor for prolonged high MTX concentration (p = 0.009, OR 5.54, 95 % CI 1.54-19.85), but not for renal dysfunction. 24241962

2013

dbSNP: rs1217691063
rs1217691063
0.040 GeneticVariation BEFREE The MTHFR C677T polymorphism plays a significant role in predisposition of renal insufficiency in diabetic patients. 23846111

2013

dbSNP: rs1217691063
rs1217691063
0.040 GeneticVariation BEFREE Sign of these predictive effects is opposite: subjects with MTHFR 677C>T polymorphism have lower likelihood of renal insufficiency; differently, wild-type MTHFR genotype subjects have lower GFR and greater hsCRP, iPTH, RRI, and LVH. 23534584

2013

dbSNP: rs1217691063
rs1217691063
0.040 GeneticVariation BEFREE We investigated plasma folate and vitamin B12, methylenetetrahydrofolate reductase (MTHFR) C677T and cystathionine beta-synthase (CBS) 844ins68 polymorphisms, and homocysteine levels before and after methionine (100 mg/kg) loading in 58 patients with angiographically documented renal artery stenosis and mildly impaired renal function. 11918280

2001