|
rs118203478
|
|
CA |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs137852832
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs137852834
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1553948516
|
|
TG |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1555487316
|
|
C |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs1567202189
|
|
CGTG |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs1569492161
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs530391015
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs771454167
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs886039813
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The T allele at MTHFR C677T was the risk factor for prolonged high MTX concentration (p = 0.009, OR 5.54, 95 % CI 1.54-19.85), but not for renal dysfunction.
|
24241962 |
2013 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The MTHFR C677T polymorphism plays a significant role in predisposition of renal insufficiency in diabetic patients.
|
23846111 |
2013 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Sign of these predictive effects is opposite: subjects with MTHFR 677C>T polymorphism have lower likelihood of renal insufficiency; differently, wild-type MTHFR genotype subjects have lower GFR and greater hsCRP, iPTH, RRI, and LVH.
|
23534584 |
2013 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We investigated plasma folate and vitamin B12, methylenetetrahydrofolate reductase (MTHFR) C677T and cystathionine beta-synthase (CBS) 844ins68 polymorphisms, and homocysteine levels before and after methionine (100 mg/kg) loading in 58 patients with angiographically documented renal artery stenosis and mildly impaired renal function.
|
11918280 |
2001 |
|
rs1800471
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Secondly, we performed a case-control orientated study to determine whether rs1800471 polymorphism and other factors influence the progression of renal impairment.
|
25298263 |
2015 |
|
rs28933979
|
|
|
0.020 |
GeneticVariation |
BEFREE |
ATTR-V30M patients with FNEs had longer disease duration (OR=1.24; 95% CI 1.07 to 1.43), renal dysfunction (OR=4.65; 95% CI 1.20 to 18.05) and were men (OR=3.57; 95% CI 1.02 to 12.30).
|
25091367 |
2015 |
|
rs699
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We analyzed single nucleotide polymorphisms (SNPs) associated with cardiovascular pathophysiology (including AGT1R T573C, AGT1R A1166C, and AGT M235T) and presence of renal dysfunction (eGFR<60 ml/min/1.73 m2) or history of CHD.
|
19327134 |
2009 |
|
rs28933979
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Renal manifestations of ATTR V30M, like other amyloidoses, are different levels of proteinuria and renal insufficiency.
|
12832749 |
2003 |
|
rs699
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
|
rs1800471
|
|
|
0.020 |
GeneticVariation |
BEFREE |
To determine whether genetic factors are involved in the development of renal dysfunction due to cyclosporine nephrotoxicity, we analyzed 2 polymorphisms in the signal sequence of the transforming growth factor (TGF)-beta 1 gene; codon 10 (Leu(10) --> Pro) and codon 25 (Arg(25) --> Pro).
|
11008076 |
2000 |
|
rs367825197
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we report the identification of a heterozygous nonsense <i>PODXL</i> mutation (c.C976T; p. Arg326X) in a Chinese pedigree featured by proteinuria and renal insufficiency with AD inheritance by whole exome sequencing (WES).
|
30523047 |
2019 |
|
rs4149056
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients with OATP1B1 521T>C mutant-type carrier had slightly higher trough SDC (0.98 ± 0.53 ng/mL) than those with wild-type carrier (0.74 ± 0.40 ng/mL) when they have repaired renal function.Heart failure patients with severe renal dysfunction (GFR<60 mL/min) and/or OATP1B1 521T>C mutant-type carriers are recommended a smaller dosage of digoxin and strict therapeutic drug monitoring.
|
30946364 |
2019 |
|
rs121918079
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This case illustrated the clinical and pathologic phenotype of an ATTR amyloidosis patient who initially presented impaired renal function and p.Leu75Pro variant was found by sequencing the coding region of TTR gene.
|
28272196 |
2017 |
|
rs138207257
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The p.Pro190Leu mutation was reported with impaired renal function at follow-up; however, the p.Gly287Val was presented with normal renal function.
|
27561601 |
2017 |
|
rs17319721
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Covariate adjustment analysis showed that the variant at rs17319721 in SHROOM3 was an independent risk factor for renal dysfunction after the first month after transplantation (P=0.022).
|
27779570 |
2017 |