Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1384093596
rs1384093596
0.700 GeneticVariation UNIPROT

dbSNP: rs1402272180
rs1402272180
0.700 GeneticVariation UNIPROT

dbSNP: rs1466858740
rs1466858740
0.700 GeneticVariation UNIPROT

dbSNP: rs1558650888
rs1558650888
A 0.700 GeneticVariation CLINVAR

dbSNP: rs1567176006
rs1567176006
G 0.700 GeneticVariation CLINVAR

dbSNP: rs17855787
rs17855787
0.700 GeneticVariation UNIPROT

dbSNP: rs371854396
rs371854396
0.700 GeneticVariation UNIPROT

dbSNP: rs375412266
rs375412266
0.700 GeneticVariation UNIPROT

dbSNP: rs757496714
rs757496714
0.700 GeneticVariation UNIPROT

dbSNP: rs770462360
rs770462360
0.700 GeneticVariation UNIPROT

dbSNP: rs779221554
rs779221554
0.700 GeneticVariation UNIPROT

dbSNP: rs371409680
rs371409680
0.010 GeneticVariation BEFREE Functional analysis of the p53 alleles present in the patient's tumor indicated that the germ-line p53(R283H) could transactivate the CDKN1A((p21, WAF1, cip1, SDI1)) but not the BAX gene and retained the ability to induce growth arrest of human glioblastoma cells. 12019170

2002

dbSNP: rs121909218
rs121909218
0.010 GeneticVariation BEFREE These results were also confirmed by expressions of Ad-wt-PTEN and Ad-G129E-PTEN in other glioblastoma cells lacking functional PTEN, U251MG, and U373MG. 12414663

2002

dbSNP: rs121912438
rs121912438
0.010 GeneticVariation BEFREE Furthermore, selective death of embryonal spinal motor neurons from G93A-SOD1 transgenic mice is induced by coculture with G93A-glioblastoma and prevented by inhibition of NO synthase. 15208263

2004

dbSNP: rs373584770
rs373584770
0.010 GeneticVariation BEFREE Activation of caspase-1 and caspase-3 is observed also in neuroblastoma lines expressing other fALS-SOD1s (G37R, G85R, and I113T) cocultured with glioblastoma lines expressing the corresponding mutant enzymes. 15208263

2004

dbSNP: rs74315452
rs74315452
0.010 GeneticVariation BEFREE Activation of caspase-1 and caspase-3 is observed also in neuroblastoma lines expressing other fALS-SOD1s (G37R, G85R, and I113T) cocultured with glioblastoma lines expressing the corresponding mutant enzymes. 15208263

2004

dbSNP: rs1045642
rs1045642
0.020 GeneticVariation BEFREE Although the C3435T polymorphism does not appear to be associated with other types of glioma, we cannot rule out that this MDR1 polymorphism may be associated with glioblastoma among men. 15947495

2005

dbSNP: rs1801275
rs1801275
0.030 GeneticVariation BEFREE In addition, IL-4RA Ser478Pro TC, CC, and IL-4RA Gln551Arg AG, AA are positively associated with GBM (OR, 1.64; 95% CI, 1.05-2.55; 1.61; 95% CI, 1.05-2.47), whereas IL-13 -1,112 CT, TT is negatively associated with GBM (0.56; 95% CI, 0.33-0.96). 16024651

2005

dbSNP: rs1805015
rs1805015
0.020 GeneticVariation BEFREE In addition, IL-4RA Ser478Pro TC, CC, and IL-4RA Gln551Arg AG, AA are positively associated with GBM (OR, 1.64; 95% CI, 1.05-2.55; 1.61; 95% CI, 1.05-2.47), whereas IL-13 -1,112 CT, TT is negatively associated with GBM (0.56; 95% CI, 0.33-0.96). 16024651

2005

dbSNP: rs1259560536
rs1259560536
0.010 GeneticVariation BEFREE In addition, IL-4RA Ser478Pro TC, CC, and IL-4RA Gln551Arg AG, AA are positively associated with GBM (OR, 1.64; 95% CI, 1.05-2.55; 1.61; 95% CI, 1.05-2.47), whereas IL-13 -1,112 CT, TT is negatively associated with GBM (0.56; 95% CI, 0.33-0.96). 16024651

2005

dbSNP: rs2017309
rs2017309
0.010 GeneticVariation BEFREE A genetic polymorphism of the CHEK2 gene (CHEK2 SNP rs2017309 A/T) was genotyped in a series of glioblastoma patients (n = 213) and population controls (n = 192). 17016233

2006

dbSNP: rs1217691063
rs1217691063
0.020 GeneticVariation BEFREE We investigated MTR c.2756A>G, MTHFR c.677C>T, and a third polymorphism, transcobalamin 2 c.776C>G (P259R), for a potential association with the formation of glioblastoma multiforme. 17119065

2006

dbSNP: rs1801198
rs1801198
0.010 GeneticVariation BEFREE We investigated MTR c.2756A>G, MTHFR c.677C>T, and a third polymorphism, transcobalamin 2 c.776C>G (P259R), for a potential association with the formation of glioblastoma multiforme. 17119065

2006

dbSNP: rs1805087
rs1805087
MTR
0.010 GeneticVariation BEFREE We investigated MTR c.2756A>G, MTHFR c.677C>T, and a third polymorphism, transcobalamin 2 c.776C>G (P259R), for a potential association with the formation of glioblastoma multiforme. 17119065

2006

dbSNP: rs3092993
rs3092993
0.010 GeneticVariation BEFREE Six hundred and eighty glioma cases (298 glioblastoma (GBM)), 503 meningioma cases, and 1555 controls recruited in the Nordic-UK Interphone study, were analysed in association with three polymorphisms in p53 (rs2287499, rs1042533, rs1625895) and five polymorphisms in ATM ( rs228599, rs3092992, rs664143, rs170548, rs3092993). 17151932

2007