Source: BEFREE ×
| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.030 | GeneticVariation | BEFREE | We report three cases that were definitively diagnosed as LM from NSCLC with a mutation of epidermal growth factor receptor (<i>EGFR</i>) L858R. | 31571928 | 2019 |
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0.030 | GeneticVariation | BEFREE | In particular, the primary mutation, L858R, potentially predicts a higher risk of LM compared with deletion of exon 19. | 30642536 | 2019 |
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|
0.030 | GeneticVariation | BEFREE | We have recently identified an EGFR mutation E884K, in combination with L858R, in a patient with advanced lung cancer who progressed on erlotinib maintenance therapy, and subsequently had leptomeningeal metastases that responded to gefitinib. | 19015641 | 2009 |