Gene: TP53 ×
Source: INFERRED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1131691003
rs1131691003
TP53
A 0.700 CausalMutation CLINVAR

dbSNP: rs1131691039
rs1131691039
TP53
T 0.700 CausalMutation CLINVAR

dbSNP: rs1131691042
rs1131691042
TP53
T 0.700 CausalMutation CLINVAR

dbSNP: rs11540652
rs11540652
TP53
T 0.700 CausalMutation CLINVAR Germline TP53 alterations in Finnish breast cancer families are rare and occur at conserved mutation-prone sites. 11139324

2001
dbSNP: rs11540652
rs11540652
TP53
T 0.700 CausalMutation CLINVAR Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study. 21601526

2011
dbSNP: rs11540652
rs11540652
TP53
T 0.700 CausalMutation CLINVAR Transcriptional functionality of germ line p53 mutants influences cancer phenotype. 17606709

2007
dbSNP: rs11540652
rs11540652
TP53
T 0.700 CausalMutation CLINVAR Gastric cancer in individuals with Li-Fraumeni syndrome. 21552135

2011
dbSNP: rs11540652
rs11540652
TP53
T 0.700 GeneticVariation CLINVAR Germ-line mutations of TP53 in Li-Fraumeni families: an extended study of 39 families. 9242456

1997
dbSNP: rs11540652
rs11540652
TP53
T 0.700 CausalMutation CLINVAR Joint effects of germ-line TP53 mutation, MDM2 SNP309, and gender on cancer risk in family studies of Li-Fraumeni syndrome. 21305319

2011
dbSNP: rs11540652
rs11540652
TP53
T 0.700 CausalMutation CLINVAR Molecular basis of the Li-Fraumeni syndrome: an update from the French LFS families. 18511570

2008
dbSNP: rs11540652
rs11540652
TP53
T 0.700 CausalMutation CLINVAR High frequency of de novo mutations in Li-Fraumeni syndrome. 19556618

2009
dbSNP: rs11540652
rs11540652
TP53
T 0.700 CausalMutation CLINVAR The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis. 23161690

2013
dbSNP: rs11540652
rs11540652
TP53
T 0.700 GeneticVariation CLINVAR Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis. 12826609

2003
dbSNP: rs11540652
rs11540652
TP53
T 0.700 CausalMutation CLINVAR Prevalence and spectrum of germline mutations of the p53 gene among patients with sarcoma. 1565143

1992
dbSNP: rs11540652
rs11540652
TP53
T 0.700 GeneticVariation CLINVAR Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes. 21343334

2011
dbSNP: rs11540652
rs11540652
TP53
T 0.700 GeneticVariation CLINVAR Transcriptional functionality of germ line p53 mutants influences cancer phenotype. 17606709

2007
dbSNP: rs121912651
rs121912651
TP53
A 0.700 CausalMutation CLINVAR Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes. 21343334

2011
dbSNP: rs121912651
rs121912651
TP53
A 0.700 CausalMutation CLINVAR Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis. 12826609

2003
dbSNP: rs121912651
rs121912651
TP53
A 0.700 CausalMutation CLINVAR Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. 1978757

1990
dbSNP: rs121912651
rs121912651
TP53
A 0.700 CausalMutation CLINVAR Transcriptional functionality of germ line p53 mutants influences cancer phenotype. 17606709

2007
dbSNP: rs121912652
rs121912652
TP53
T 0.700 CausalMutation CLINVAR

dbSNP: rs121912653
rs121912653
TP53
G 0.700 CausalMutation CLINVAR

dbSNP: rs121912656
rs121912656
TP53
T 0.700 CausalMutation CLINVAR

dbSNP: rs121912657
rs121912657
TP53
A 0.700 CausalMutation CLINVAR

dbSNP: rs121912662
rs121912662
TP53
G 0.700 CausalMutation CLINVAR