Source: CLINVAR ×
Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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A | 0.700 | CausalMutation | CLINVAR | Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability. | 23108399 | 2013 |
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A | 0.700 | CausalMutation | CLINVAR | The first mutations in the MYH gene reported in Moroccan colon cancer patients. | 22266422 | 2012 |
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A | 0.700 | CausalMutation | CLINVAR | Expanded extracolonic tumor spectrum in MUTYH-associated polyposis. | 19732775 | 2009 |
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A | 0.700 | CausalMutation | CLINVAR | Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis. | 19032956 | 2009 |
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A | 0.700 | CausalMutation | CLINVAR | High frequency of copy-neutral LOH in MUTYH-associated polyposis carcinomas. | 18506705 | 2008 |
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A | 0.700 | CausalMutation | CLINVAR | Characterization of mutant MUTYH proteins associated with familial colorectal cancer. | 18534194 | 2008 |
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A | 0.700 | CausalMutation | CLINVAR | Germline MYH mutations in a clinic-based series of Canadian multiple colorectal adenoma patients. | 17219385 | 2007 |
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A | 0.700 | CausalMutation | CLINVAR | MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype. | 16557584 | 2006 |
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A | 0.700 | CausalMutation | CLINVAR | Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair. | 15987719 | 2005 |
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A | 0.700 | CausalMutation | CLINVAR | Multiplicity in polyp count and extracolonic manifestations in 40 Dutch patients with MYH associated polyposis coli (MAP). | 16140997 | 2005 |
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A | 0.700 | CausalMutation | CLINVAR | Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. | 12606733 | 2003 |