|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia coli Strain.
|
25820570 |
2015 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability.
|
23108399 |
2013 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Identification of a patient with atypical MUTYH-associated polyposis through detection of the KRAS c.34G>T mutation in liver metastasis.
|
23341527 |
2013 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Integrative analysis of hereditary nonpolyposis colorectal cancer: the contribution of allele-specific expression and other assays to diagnostic algorithms.
|
24278394 |
2013 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer.
|
20848659 |
2010 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay.
|
19953527 |
2010 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis.
|
20418187 |
2010 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Structural constraints and the importance of lipophilicity for the mitochondrial uncoupling activity of naturally occurring caffeic acid esters with potential for the treatment of insulin resistance.
|
19732755 |
2010 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas.
|
19527492 |
2009 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
APC or MUTYH mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas.
|
19793053 |
2009 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Expanded extracolonic tumor spectrum in MUTYH-associated polyposis.
|
19732775 |
2009 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Heterogeneous molecular mechanisms underlie attenuated familial adenomatous polyposis.
|
18091433 |
2007 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Immunohistochemical expression of MYH protein can be used to identify patients with MYH-associated polyposis.
|
16890597 |
2006 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
The role of MYH and microsatellite instability in the development of sporadic colorectal cancer.
|
17031395 |
2006 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Increased frequency of disease-causing MYH mutations in colon cancer families.
|
16774938 |
2006 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype.
|
16557584 |
2006 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
The potential for increased clinical sensitivity in genetic testing for polyposis colorectal cancer through the analysis of MYH mutations in North American patients.
|
15635083 |
2005 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Mutations of APC and MYH in unrelated Italian patients with adenomatous polyposis coli.
|
16134147 |
2005 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas.
|
14999774 |
2004 |
|
rs587778541
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.
|
12707038 |
2003 |