Gene: SDHC ×
Source: CURATED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1553264218
rs1553264218
SDHC
C 0.700 CausalMutation CLINVAR

dbSNP: rs1558182956
rs1558182956
SDHC
T 0.700 GeneticVariation CLINVAR

dbSNP: rs587776653
rs587776653
SDHC
T 0.700 CausalMutation CLINVAR

dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR A comprehensive next generation sequencing-based genetic testing strategy to improve diagnosis of inherited pheochromocytoma and paraganglioma. 23666964

2013
dbSNP: rs764575966
rs764575966
SDHC
T 0.700 CausalMutation CLINVAR A SDHC Founder Mutation Causes Paragangliomas (PGLs) in the French Canadians: New Insights on the SDHC-Related PGL. 27700540

2016
dbSNP: rs587776653
rs587776653
SDHC
T 0.700 GeneticVariation CLINVAR An Alu-mediated partial SDHC deletion causes familial and sporadic paraganglioma. 15342702

2004
dbSNP: rs587776653
rs587776653
SDHC
T 0.700 GeneticVariation CLINVAR Autosomal dominant malignant and catecholamine-producing paraganglioma caused by a splice donor site mutation in SDHC. 12658451

2003
dbSNP: rs587776653
rs587776653
SDHC
C 0.700 GeneticVariation CLINVAR Autosomal dominant malignant and catecholamine-producing paraganglioma caused by a splice donor site mutation in SDHC. 12658451

2003
dbSNP: rs587776652
rs587776652
SDHC
A 0.700 CausalMutation CLINVAR Biallelic inactivation of the SDHC gene in renal carcinoma associated with paraganglioma syndrome type 3. 22351710

2012
dbSNP: rs755235380
rs755235380
SDHC
G 0.700 CausalMutation CLINVAR Biallelic inactivation of the SDHC gene in renal carcinoma associated with paraganglioma syndrome type 3. 22351710

2012
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD. 17667967

2008
dbSNP: rs587776653
rs587776653
SDHC
T 0.700 GeneticVariation CLINVAR Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD. 17667967

2008
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs755235380
rs755235380
SDHC
G 0.700 CausalMutation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Exploring the association of succinate dehydrogenase complex mutations with lymphoid malignancies. 24781345

2014
dbSNP: rs587776653
rs587776653
SDHC
T 0.700 GeneticVariation CLINVAR Functional cardiac paraganglioma associated with a rare SDHC mutation. 24402737

2014
dbSNP: rs764575966
rs764575966
SDHC
T 0.700 CausalMutation CLINVAR Germline mutations in PTEN and SDHC in a woman with epithelial thyroid cancer and carotid paraganglioma. 17898811

2007
dbSNP: rs587778661
rs587778661
SDHC
T 0.700 GeneticVariation CLINVAR Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients. 27279923

2016
dbSNP: rs755235380
rs755235380
SDHC
G 0.700 CausalMutation CLINVAR Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. 23282968

2013
dbSNP: rs764575966
rs764575966
SDHC
T 0.700 CausalMutation CLINVAR Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. 23282968

2013
dbSNP: rs201286421
rs201286421
SDHC
T 0.700 CausalMutation CLINVAR Long-delayed localization of a cardiac functional paraganglioma with SDHC mutation. 22868853

2012
dbSNP: rs587776652
rs587776652
SDHC
A 0.700 CausalMutation CLINVAR Mutations in SDHC cause autosomal dominant paraganglioma, type 3. 11062460

2000
dbSNP: rs755235380
rs755235380
SDHC
G 0.700 CausalMutation CLINVAR Mutations in SDHC cause autosomal dominant paraganglioma, type 3. 11062460

2000
dbSNP: rs764575966
rs764575966
SDHC
T 0.700 CausalMutation CLINVAR Phenotypic variability and risk of malignancy in SDHC-linked paragangliomas: lessons from three unrelated cases with an identical germline mutation (p.Arg133*). 24423348

2014