|
rs1553565140
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs4953348
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs4953348 polymorphism of EPAS1 gene had a significant correlation with the SaO2 level and AMS, and a significant difference in the AG and GG genotype distribution between the AMS and non-AMS groups.
|
27982053 |
2016 |
|
rs12406290
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriers of the "GG" haplotype of rs12406290-rs2153364 exhibited an increased risk of AMS after adjustments for age and smoking status.
|
25431923 |
2014 |
|
rs12757362
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant association was noted between AMS and rs12757362, rs1339894, rs1361384, rs2009873, rs2739513 or rs2486729 before and after Bonferroni correction.
|
25431923 |
2014 |
|
rs2153364
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriers of the "GG" haplotype of rs12406290-rs2153364 exhibited an increased risk of AMS after adjustments for age and smoking status.
|
25431923 |
2014 |
|
rs480902
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Age was found to be significantly associated with the EPAS1 SNP in the CMS patients while heart rate (HR) and oxygen saturation level of hemoglobin (SaO(2)) were found to be significantly associated with the EGLN1 (rs480902) SNP in the Han patients with AMS.
|
22595196 |
2012 |
|
rs1413711
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs3025039 SNP and the haplotype (rs1413711, rs833070 and rs3025000) in the VEGFA gene were significantly associated with AMS (p = 0.0435 and 0.024, respectively).
|
21242666 |
2011 |
|
rs3025000
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs3025039 SNP and the haplotype (rs1413711, rs833070 and rs3025000) in the VEGFA gene were significantly associated with AMS (p = 0.0435 and 0.024, respectively).
|
21242666 |
2011 |
|
rs3025039
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs3025039 SNP and the haplotype (rs1413711, rs833070 and rs3025000) in the VEGFA gene were significantly associated with AMS (p = 0.0435 and 0.024, respectively).
|
21242666 |
2011 |
|
rs833070
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs3025039 SNP and the haplotype (rs1413711, rs833070 and rs3025000) in the VEGFA gene were significantly associated with AMS (p = 0.0435 and 0.024, respectively).
|
21242666 |
2011 |
|
rs1267969615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ACE (I/D) was significantly associated with HR in CMS patients while the AGT M235T was significantly associated with SaO(2) and BPs/d in AMS patients.
|
20570668 |
2010 |
|
rs1799722
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We tested this by looking for associations between two functional polymorphisms (the in/del polymorphism +9/-9 [rs5810761] and the single-nucleotide polymorphism C--58T [rs1799722]) of BDKRB2 (the gene encoding the bradykinin receptor B2) and susceptibility to AMS in an altitude-exposed Nepalese population.
|
20511677 |
2010 |
|
rs699
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ACE (I/D) was significantly associated with HR in CMS patients while the AGT M235T was significantly associated with SaO(2) and BPs/d in AMS patients.
|
20570668 |
2010 |
|
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We tested the hypothesis that haplotypes, as determined by tagSNPs, in NOS3 would be differentially represented in individuals with and without AMS sampled at the Janai Purnima Festival at Lake Gosain Kunda, Nepal, at 4380 m. Seven SNPs were tested, and a highly significant association (p = 0.004) was found for genotypes of the commonly studied missense polymorphism Glu298Asp (rs 1799983; G/T transversion at base 894).
|
19775216 |
2009 |